Application of urine biomarker detection reagent in preparation of new coronal pneumonia diagnostic kit
A technology of biomarkers and detection reagents, which is applied in the field of in vitro diagnostic reagents, can solve the problems of high infection risk, irregular sampling, and physical discomfort of sampling personnel, so as to reduce the risk of infection, reduce testing costs, and reduce urine indicators Effect
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[0027] Embodiment 1 The device of the present invention for diagnosing new coronary pneumonia
[0028] 1) Detection device; the detection device includes a high performance liquid chromatography-time-of-flight mass spectrometer; the detection device has built-in reagents for detecting the following biomarkers in urine: oxoglutaric acid, indoxyl and 2-phenylacetamide ;
[0029] 2) Analysis device;
[0030] The analysis device has a built-in data input port for receiving the detection result of the aforementioned detection device, that is, the abundance value of the biomarker;
[0031] The analysis device has a built-in random forest algorithm, which can distinguish between new coronary pneumonia and non-new coronary pneumonia based on the detection results of oxoglutaric acid, indoxyl and 2-phenylacetamide in the urine of known new coronary pneumonia and non-new coronary pneumonia groups. A binary classification model of pneumonia;
[0032] The analysis device can also subst...
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