Application of cinnamon essential oil in preparation of bacteriostatic drugs

A technology of cinnamon essential oil and uses, applied in the field of medicine, can solve the problems of serious side effects and the like

Active Publication Date: 2022-05-27
SANYA QIXING BIOLOGICAL ENERGY DEV CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] In the prior art, the abuse of antibiotics is not uncommon, and the side effects caused by the abuse of antibiotics are also becoming more and more serious

Method used

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  • Application of cinnamon essential oil in preparation of bacteriostatic drugs
  • Application of cinnamon essential oil in preparation of bacteriostatic drugs
  • Application of cinnamon essential oil in preparation of bacteriostatic drugs

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0055] Use of cinnamon essential oil in the preparation of antibacterial drugs. The bacterial species is Burkholderia mallei, Burkholderia mallei or Burkholderia cepacia.

Embodiment 2

[0057] How to prepare cinnamon essential oil:

[0058] There are many extraction methods for cinnamon essential oil, such as microwave-assisted steam distillation, ultrasonic-assisted extraction, supercritical carbon dioxide extraction, molecular distillation, etc., but not limited to this.

[0059] Taking ultrasonic-assisted distillation as an example, the extraction process is briefly described as follows:

[0060] (1) Pulverize the cinnamon, pass it through a 50-mesh sieve, take 50 g of the powder and place it in a flask, add 500 mL of water, and place it in an ultrasonicator for 10 minutes.

[0061] (2) Distillation, the distillate is collected in a conical flask through a water condenser.

[0062] (3) Transfer the above-mentioned liquid to a separatory funnel, let it stand for stratification, separate the liquids, and discard the lower layer to obtain a golden yellow liquid, which is the crude cinnamon essential oil.

[0063] (4) Transfer the above crude product to a co...

Embodiment 3

[0065] The technical index of cinnamon essential oil is as follows (obtained in Example 2):

[0066] Cinnamon essential oil is a yellow to reddish-brown clear liquid, slightly soluble in water, easily soluble in ethanol, glacial acetic acid, and insoluble in glycerol and mineral oil.

[0067] Cinnamon essential oil contains a variety of active ingredients. The origin, collection time, extraction site, extraction method and detection method of cinnamon raw materials have certain influence on the chemical composition of cinnamon essential oil.

[0068] The test results of cinnamon essential oil are as follows in Table 7 (see attached Figure 40 ):

[0069] Table 7

[0070]

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PUM

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Abstract

The invention relates to application of cinnamon essential oil in preparation of bacteriostatic drugs, and belongs to the technical field of medicines. The strain is Burkholderia pseudomallei and Burkholderia cepacia, and the strain is Burkholderia pseudomallei. The cinnamon essential oil can effectively inhibit burkholderia pseudomallei and burkholderia cepacia as a special bacteriostatic agent, the cinnamon essential oil is used as the bacteriostatic agent, dependence of human beings on antibiotics is certainly relieved, a certain foundation is laid for research and development of Chinese herbal medicines, and clinical application significance is achieved. The medicine is a clinical treatment medicine with high efficiency, small toxic and side effects and even no toxic and side effects.

Description

technical field [0001] The invention relates to the use of cinnamon essential oil in preparing antibacterial drugs, and belongs to the technical field of medicine. Background technique [0002] In the prior art, the abuse of antibiotics is not uncommon, and the side effects caused by the abuse of antibiotics are becoming more and more serious. [0003] Burkholderia melioidosis and Burkholderia cepacia are pathogens related to human diseases, which seriously endanger human health and life safety, and drug resistance is gradually increasing. Such bacteria are widely prevalent in southern my country, and the fatality rate is high. [0004] Therefore, there is an urgent need to find a safe and effective drug with less side effects to replace traditional antibiotics to solve the above technical problems. SUMMARY OF THE INVENTION [0005] The object of the present invention is to provide the use of a kind of cinnamon essential oil in the preparation of antibacterial medicine. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/54A61P31/04
CPCA61K36/54A61P31/04Y02A50/30
Inventor 王玉丰邓一鸣邓成儒陈如寿靳成达肖培富
Owner SANYA QIXING BIOLOGICAL ENERGY DEV CO LTD
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