Hyaluronic acid oral liquid easy to absorb and application
A technology of hyaluronic acid and hyaluronate, which is applied in the fields of application, function of food ingredients, food ingredients containing natural extracts, etc., can solve problems such as slow onset of action, difficulty in absorbing hyaluronic acid, loss of effect, etc., to achieve Quick onset, good moisturizing effect, easy absorption effect
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preparation example Construction
[0053]The preparation method of the centella asiatica extract comprises the following steps: soaking the centella asiatica in water, heating and refluxing at 80°C for 20 hours, and then filtering successively, concentrating the filtrate, and drying to obtain the centella asiatica extract.
[0054] The preparation method of the aloe extract comprises the following steps: after squeezing the aloe, concentrating the squeezed solution at 70° C. for 15 hours, and drying the concentrated solution in a vacuum to obtain the aloe extract.
[0055] The preparation method of the pomegranate extract comprises the following steps: soaking the pomegranate peel, pomegranate pulp and pomegranate seeds in water, performing ultrasonic extraction at 40° C. for 10 hours, filtering in sequence, concentrating the filtrate, and drying to obtain the pomegranate extract.
Embodiment 1
[0057] The mass percentage of each component of Example 1 in the hyaluronic acid oral solution is shown in Table 1 below. The preparation process of the hyaluronic acid oral liquid of embodiment 1 is as follows:
[0058] (1) Under the condition of maintaining room temperature, slowly add the components shown in Table 1 into 35°C water according to the above proportions, mix and stir evenly until completely dissolved;
[0059] (2) Ultrasonic is carried out to oral liquid, and the temperature of ultrasonic is 50 ℃, and the power of ultrasonic is 300W;
[0060] (3) The oral liquid after ultrasonication is membrane-filtered with a nylon membrane with a pore size of 0.22 μm;
[0061] (4) cooling process is carried out to oral liquid, the temperature of oral liquid is cooled to below room temperature;
[0062] (5) Aseptic filling is adopted;
[0063] Specifically, a high-voltage pulsed electric field (field strength of 50K / cm, pulse number of 350, and pulse frequency of 450Hz) wa...
Embodiment 2~ Embodiment 5
[0066] Embodiment 2~Example 5, Comparative Examples 1~5
[0067] The oral liquid was prepared according to the component formula shown in Table 1, and the operating conditions of the preparation method were all the same as in Example 1.
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