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Traditional Chinese medicine composition for treating cholelithiasis and preparation method and application thereof

A composition and a technology for cholelithiasis, which are applied in the directions of drug combinations, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve the problems of cholelithiasis troubled by the recurrence rate and reoperation rate of stones, low stone expulsion rate, and easy recurrence. , to achieve the effect of inhibiting platelet aggregation, qi and blood harmony, and zang-fu organs.

Active Publication Date: 2022-03-18
THE CHINESE TRADITIONAL HERB MEDICINE RES INST HENAN PROV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Tauroursodeoxycholic acid capsule is currently the fastest stone-dissolving drug with the most definite curative effect in the world. The effective rate is about 60%. burden
Surgical treatment for sediment-shaped, small-particle multiple stones is not satisfactory, and the incidence of postoperative complications (such as bile leakage, residual stones in the biliary tract, colon cancer, acute pancreatitis, and abdominal suppurative infection, etc.) Stone recurrence rate and reoperation rate are still the main problems that plague the western medicine treatment of cholelithiasis
[0004] Although the traditional Chinese medicine treatment of cholelithiasis has many advantages, there are also the following points: 1. There are not many studies on Chinese patent medicines for the treatment of cholelithiasis and Chinese herbal compound, and the design of clinical randomized controlled trials in clinical reports is unscientific. Incompleteness, etc., affect the authenticity and accuracy of the test results, so the common Chinese patent medicines for removing stones and dissolving stones are not accurate; 2. In recent years, it has been reported in literature that the traditional Chinese medicine treatment of cholelithiasis is unilateral or auricular point, electroacupuncture and other methods Used alone, the stone removal rate is low

Method used

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  • Traditional Chinese medicine composition for treating cholelithiasis and preparation method and application thereof
  • Traditional Chinese medicine composition for treating cholelithiasis and preparation method and application thereof

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Effect test

Embodiment 1

[0035] The embodiment of the present invention provides a traditional Chinese medicine composition for the treatment of cholelithiasis. The traditional Chinese medicine composition is composed of the following raw materials in parts by weight: Angelica 20g, Radix Paeoniae Alba 20g, Bupleurum 10g, Radix Paeoniae Rubra 20g, Gallinarum 15g, Curcuma 10g, Desmodium 15g, Haijinsha 30g, Rhubarb 6g, Salvia miltiorrhiza 30g, Saponaria thorn 10g, Toosendan 10g, Woody fragrance 10g, Qingpi 10g, Tangerine peel 10g, Zhilicorice 6g.

[0036] The preparation method of the above-mentioned traditional Chinese medicine composition, the specific steps are: take each raw material drug plus water twice the total mass of the raw material drug and soak for 0.5 to 2 hours, boil it with strong fire, turn to slow fire and decoct for 0.5 hour, filter the liquid, add the filter residue The water twice the total mass of the raw material drug is decocted once in the same way, and the filtrates are combined ...

Embodiment 2

[0038] The embodiment of the present invention provides a traditional Chinese medicine composition for treating cholelithiasis. 14 parts of Neijin, 9 parts of Turmeric, 14 parts of Desmodium, 27 parts of Haijinsha, 5 parts of Rhubarb, 27 parts of Salvia, 9 parts of saponins, 9 parts of Toosendan, 9 parts of woody fragrance, 9 parts of green bark, and tangerine peel 9 parts, Zhi Licorice 5 parts.

[0039] The preparation method of the above-mentioned traditional Chinese medicine composition, the specific steps are: take each raw material drug plus water twice the total mass of the raw material drug and soak for 0.5 to 2 hours, boil it with strong fire, turn to slow fire and decoct for 0.5 hour, filter the liquid, add the filter residue The water twice the total mass of the raw material drug is decocted once in the same way, and the filtrates are combined to obtain the product.

Embodiment 3

[0041] The embodiment of the present invention provides a traditional Chinese medicine composition for treating cholelithiasis. 16 parts of Neijin, 11 parts of Turmeric, 16 parts of Desmodium, 33 parts of Haijinsha, 7 parts of Rhubarb, 33 parts of Salvia, 11 parts of saponins, 11 parts of Toosendan, 11 parts of woody fragrance, 11 parts of green bark, tangerine peel 11 parts, 7 parts of roasted licorice.

[0042] The preparation method of the above-mentioned traditional Chinese medicine composition, the specific steps are: take each raw material drug plus water twice the total mass of the raw material drug and soak it for 0.5 to 2 hours, boil it with a strong fire, turn to a slow fire and decoct it for 1 hour, filter the liquid, add the raw material to the filter residue Water with 4 times the total weight of the drug is decocted once in the same way, and the filtrates are combined.

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Abstract

The invention discloses a traditional Chinese medicine composition for treating cholelithiasis and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 18-22 parts of angelica sinensis, 18-22 parts of radix paeoniae alba, 9-11 parts of radix bupleuri, 18-22 parts of radix paeoniae rubra, 14-16 parts of endothelium corneum gigeriae galli, 9-11 parts of radix curcumae, 14-16 parts of lysimachia christinae hance, 27-33 parts of lygodium japonicum, 5-7 parts of rheum officinale, 27-33 parts of salvia miltiorrhiza, 9-11 parts of spina gleditsiae, 9-11 parts of szechwan chinaberry fruit, 9-11 parts of elecampane, 9-11 parts of pericarpium citri reticulatae viride, 9-11 parts of pericarpium citri reticulatae and 5-7 parts of honey-fried licorice root. The raw materials in the traditional Chinese medicine composition are compatible with one another, the curative effect on cholelithiasis is definite in combination with auricular point therapy, symptoms can be effectively improved, pain of patients can be effectively relieved, and the traditional Chinese medicine composition is effective, low in price, easy to operate, wide in applicability and worthy of popularization.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition for treating cholelithiasis, a preparation method and application thereof. Background technique [0002] Cholelithiasis is one of the common and frequently-occurring diseases in clinical gastroenterology. After the formation of gallstones in the gallbladder, it can stimulate the gallbladder mucosa, which can not only cause chronic inflammation of the gallbladder, but also cause chronic inflammation of the gallbladder when the stones are embedded in the neck of the gallbladder or the cystic duct. Can cause secondary infection, leading to acute inflammation of the gallbladder. Chronic stimulation of the gallbladder mucosa by stones may also lead to the occurrence of gallbladder cancer. It has been reported that the incidence of gallbladder cancer can reach 1% to 2%, and more than 96% of gallbladder cancer p...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P1/16A61K35/57
CPCA61K36/232A61K36/71A61K36/65A61K36/233A61K35/57A61K36/9066A61K36/185A61K36/53A61K36/12A61K36/708A61K36/537A61K36/483A61K36/58A61K36/285A61K36/752A61K36/484A61P1/16A61K2236/331A61K2236/39Y02A50/30
Inventor 娄静赵雷王菲朱岩洁张杭洲袁帅强徐娇娇侯留法
Owner THE CHINESE TRADITIONAL HERB MEDICINE RES INST HENAN PROV
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