Application of hyperoside in preparation of medicine for preventing and treating retina degenerative diseases
A technology of retinal degeneration and hyperin, applied in the field of medicine, can solve problems such as unreported hyperin activity, and achieve the effect of treating and improving retinal degeneration and significant retinal degeneration
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[0039] In this example, the intervention effect of hyperoside on a mouse model of retinal photodamage was clarified through non-invasive retinal fundus tomography OCT technology, pathology and immunohistochemistry research methods. The research results show that hyperoside can effectively interfere with the death of photoreceptor cells and the occurrence of retinal degeneration, and play a significant protective effect on the structure of the retina.
[0040] 1. Method
[0041] 1. Drugs
[0042] Hyperin: purchased from Shanghai Yuanye Biotechnology Co., Ltd., 482-36-0, Lot#Y08N9X74602, purity ≥ 98%.
[0043] 2. Animal models
[0044] Six-week-old female Balb / c mice (Slack, Shanghai) were used for the experiment. Mice were randomly divided into normal control group, photodamage model control group and hyperin treatment group. Among them, the mice in the normal control group and the mice in the photodamage model control group received 100 μL of 0.5% sodium carboxymethylcellu...
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