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A sample analyzer and counting method thereof

A technology of sample analyzer and counting method, applied in the field of sample analysis, can solve the problems of wrong and unreliable basophil counting

Active Publication Date: 2022-06-21
SHENZHEN DYMIND BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The blood cell analyzer in the prior art measures the count of basophils in the sample through a single optical detection channel, wherein the basophils overlap with neutrophils and eosinophils in size and shape. Incorrect basophil counts in the presence of other abnormal particles in the basophil area of
[0004] Alternatively, the hematology analyzer in the prior art measures the basophil count of the sample through a single impedance detection channel, which is easily affected by immature granulocytes, lipid particles, or channel micropore clogging, resulting in basophils wrong count
[0005] Therefore, the blood cell analyzer in the prior art obtains the count value of basophils through a single channel, which has the problem of unreliability

Method used

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  • A sample analyzer and counting method thereof
  • A sample analyzer and counting method thereof
  • A sample analyzer and counting method thereof

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Embodiment Construction

[0031] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present application. It should be understood that the specific embodiments described herein are only used to explain the present application, but not to limit the present application. In addition, it should be noted that, for the convenience of description, the drawings only show some but not all structures related to the present application. Based on the embodiments in this application, all other embodiments obtained by those of ordinary skill in the art without creative work fall within the protection scope of this application.

[0032] The terms "first", "second", etc. in this application are used to distinguish different objects, rather than to describe a specific order. Furthermore, the terms "comprising" and "having", and any variations thereof, are intended to cover non-exclusiv...

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Abstract

The application discloses a sample analyzer and its counting method. The sample analyzer includes a control module, a first detection module and a second detection module. The control module is respectively connected to the first detection module and the second detection module. The counting method includes: The control module generates a first histogram based on the first measurement data of the first detection module; the control module obtains an area ratio based on the ratio of the first area to the total area of ​​the first histogram; the control module calculates the number of discrete particles in the second The number ratio of white blood cells in the detection module; the control module obtains the positive probability value of the sample based on multiple area ratios and number ratios; the control module obtains the proportion of basophils in white blood cells based on the positive probability value. Through the above method, the positive misjudgment rate of the sample can be reduced, the positive detection rate of the sample can be increased, and the reliability of the count value of basophils can be improved.

Description

technical field [0001] The present application relates to the technical field of sample analysis, and in particular, to a sample analyzer and a counting method thereof. Background technique [0002] The blood cell analyzer is an instrument for classifying and counting blood cells. Usually, the blood cell analyzer can divide white blood cells into five groups: lymphocytes, monocytes, neutrophils, eosinophils and basophils. It counts. [0003] The prior art blood cell analyzer measures the basophil count of a sample through a single optical detection channel, wherein the basophils overlap with neutrophils and eosinophils in size and shape, and in the sample In the presence of other abnormal particles in the basophilic area of ​​​​the [0004] Alternatively, the prior art hematology analyzer measures the basophil count of a sample through a single impedance detection channel, which is easily affected by immature granulocytes, lipid particles, or blockage of channel pores, res...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N15/10G06K9/00
CPCG01N15/1012G01N15/1031G01N2015/1006G06F2218/08G06F2218/12
Inventor 方建伟李国军杨清云徐宏勋
Owner SHENZHEN DYMIND BIOTECH
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