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Natural Sanzan gum with alcohol solubility and moisture retention, washing-free disinfection gel and application thereof

A technology of disinfection gel and sanzan gel, which is applied in the field of natural sanzan gel and disposable disinfection gel, can solve the problems of easy flocculation, poor compatibility and stability, etc.

Active Publication Date: 2022-02-08
NANKAI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, gel thickeners such as cellulose and carbomer have poor compatibility and stability with disinfectants such as ethanol and isopropanol.
At present, there are few natural product polysaccharides used as gelling agents and thickeners for the preparation of hand sanitizer gels. The main reason is that natural gel thickeners are insoluble in fat-soluble reagents such as ethanol and isopropanol, and are easy to flocculate to form precipitates.

Method used

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  • Natural Sanzan gum with alcohol solubility and moisture retention, washing-free disinfection gel and application thereof
  • Natural Sanzan gum with alcohol solubility and moisture retention, washing-free disinfection gel and application thereof
  • Natural Sanzan gum with alcohol solubility and moisture retention, washing-free disinfection gel and application thereof

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preparation example Construction

[0055] The present invention provides the preparation method of described no-wash disinfection gel, comprises the following steps:

[0056] 1) dissolving the natural sanzan gum in water to obtain a sanzan gum solution;

[0057] 2) Mix the sanzan gum solution in step 1) with disinfectant and cation to obtain mixed solution 1;

[0058] 3) mixing ethanol and fragrance to obtain mixed solution 2;

[0059] 4) Mix the mixed solution 1 in step 2) and the mixed solution 2 in step 3), heat at 75-90°C, and cool to obtain a no-clean disinfection gel;

[0060] There is no time sequence limitation between steps 1)-2) and step 3).

[0061] The invention dissolves the natural sanzan gum in water to obtain a sanzan gum solution.

[0062] In the present invention, the mass percent content of the prepared sanzan gum solution is preferably 0.15-0.3%, more preferably 0.2-0.25%.

[0063] After obtaining the Sanzan gum solution, the present invention mixes the Sanzan gum solution with a disinfe...

Embodiment 1

[0073] Ethanol Solubility Experiment of Sanzan Gum

[0074] 1) The original high acyl sanzan gum was fermented by Sphingomonas T-3 (CGMCC No.10150), and the transparent high acyl sanzan gum was fermented by Sphingomonas NXdP (CGMCC No.15406) , using Sphingomonas T-4 (CGMCC No.22948) to produce low acyl sanzan gum;

[0075] 2) Take the original high-acyl Sanzan gum, transparent high-acyl Sanzan gum and low-acyl Sanzan gum to prepare aqueous solutions with concentrations of 0.02%, 0.1%, 1% and 3%, respectively;

[0076] 3) Mix the different kinds of Sanzan gum aqueous solutions with different concentrations prepared above according to the volume ratio of 1:1 and 0.1:1, and stir evenly. Observe the inside of the tubes and find that there is no precipitation in each tube, indicating that the Sanzan gum solution can be miscible with ethanol and has alcohol-soluble properties.

[0077] (4) Heat the above aqueous solution of Sanzan Gum at 90°C for 10-30 minutes, and cool naturally ...

Embodiment 2

[0079] Determination of moisturizing performance of natural product polysaccharide Sanzan gum, the specific method is as follows:

[0080] (1) 3 parts of each of 3 kinds of natural sanzan gums, sodium hyaluronate, and glycerin in the embodiment 1 of taking 0.5 g are weighed in a weighing bottle;

[0081] (2) Add 0.2g of distilled water. After the sample has fully absorbed water, place it in a desiccator equipped with silica gel, place it at room temperature, and weigh it after 3, 6, 9, 18, 21, and 24 hours respectively, and calculate the average of 3 times. Value, calculate moisture retention rate by formula I:

[0082] Moisture retention rate (%) = H n / H o ×100% Formula I

[0083] Among them, H n is the water quality of samples at different times (unit: g); H o is the initial water mass of the sample (unit: g).

[0084] The three kinds of Sanzan gums in Example 1 have the same moisturizing properties as hyaluronic acid, and after being placed for 24 hours, they have a ...

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Abstract

The invention provides natural Sanzan gum with alcohol solubility and moisture retention, washing-free disinfection gel and application thereof, and belongs to the technical field of hygiene and disinfection articles. The natural Sanzan gum is a natural product polysaccharide generated by sphingomonas, has the characteristics of alcohol solubility, moisture retention, gelling property, thickening property, emulsifying property and the like, can be used as a natural gel thickener to be applied to products such as hand-washing-free disinfection gel, cosmetics and the like, and has the characteristics of greenness, safety and stability. The washing-free disinfection gel containing the natural Sanzan gum is free of hand washing, can kill pathogenic microorganisms, has the characteristics of disinfection, sterilization, skin care, greenness, safety, comfort and the like, and is a novel washing-free disinfection gel suitable for being used by medical personnel and families.

Description

technical field [0001] The invention belongs to the technical field of sanitation and disinfection products, and in particular relates to a natural sanzan gum with alcohol solubility and moisture retention, a wash-free disinfection gel and its application. Background technique [0002] Disinfectant gel is easy to use and effective, and can effectively remove bacteria on hands. It is a disinfection product with ethanol, biguanide disinfectant, quaternary ammonium salt disinfectant, etc. as the main active ingredients. It can kill microorganisms with Enteropathogenic bacteria, pyogenic cocci, pathogenic yeast and common bacteria in hospital infection, suitable for surgical hand disinfection and hygienic hand disinfection. Disposable disinfection gel is widely used because it can effectively eliminate hand germs without washing with water, and it is easy to carry and use. [0003] At present, the disposable disinfectant gel on the market is mainly composed of three parts: gel ...

Claims

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Application Information

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IPC IPC(8): A61K8/73A61K8/99A61K8/19A61K8/41A61K8/43A61K8/04A61Q19/10A61Q17/00A61Q19/00
CPCA61K8/73A61K8/99A61K8/19A61K8/416A61K8/43A61K8/042A61Q19/10A61Q17/005A61Q19/00A61K2800/48
Inventor 马挺吴萌萌李国强石壮壮明月
Owner NANKAI UNIV
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