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Whitening effervescent mask using radix angelicae as main drug and preparation method thereof

A technology for effervescent facial mask and whitening, applied in the field of effervescent facial mask and preparation thereof

Pending Publication Date: 2022-02-01
霍清
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] Masks are widely used because they are easy to carry and use, and have a high degree of recognition. The mask products currently on the market are mainly divided into two types: patch type and tear-off type. Most products contain liquid or gel. For many For masks containing active ingredients, shelf life and storage are still an issue to be addressed

Method used

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  • Whitening effervescent mask using radix angelicae as main drug and preparation method thereof
  • Whitening effervescent mask using radix angelicae as main drug and preparation method thereof
  • Whitening effervescent mask using radix angelicae as main drug and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Weigh 100g of soybean oil, 18g of refined egg yolk lecithin, and 32g of oleic acid according to the prescription, shear at high speed for 2 minutes, heat in a water bath to 50-60°C, stir until dissolved, and protect with nitrogen during the heating process to obtain an oil phase. Weigh 25g of glycerin, 5g of Angelica dahurica extract, 10g of Baishui root extract, and an appropriate amount of water to 1000mL, heat to 50-60°C, stir until dissolved and set aside. The obtained oil phase was slowly poured into the water phase, and at the same time, high-speed shearing was performed at a speed of 10,000 rpm for 10 minutes to obtain colostrum. The colostrum is homogenized by a high-pressure homogenizer, once with a low pressure of 200bar, and 8 times with a high pressure of 1000bar. The homogenization can be stopped when the particle size reaches about 180nm, and then the pressure is reduced. The temperature of the emulsion was kept at 40°C during the homogenization process. ...

Embodiment 2

[0051] Prescription of whitening effervescent mask: the main drug is Angelica dahurica, the auxiliary drugs are bletilla striata and bletilla, and the auxiliary materials are corn starch, hydroxypropyl methylcellulose (HPMC), sodium bicarbonate (NaHCO 3 ), citric acid (C 6 h 8 o 7 ·H 2 O), talcum powder, because Angelica dahurica has photosensitivity, so choose medicine powder and extract to use simultaneously, bletilla striata is natural colloid, not easy to extract, so bletilla striata directly adopts medicine powder to make component use, the molding of effervescent mask and corresponding characteristics are all affected by auxiliary materials Influenced by the amount of usage, three kinds of prescriptions with different proportions are designed, as shown in Table 2, the Angelica dahurica extract and the Radix Radix Radix Radix Radix Radix Radix L. L. extract and the Radix Radix Radix Radix Radix L. extract are embedded in liposomes in prescription 3, and are prepared usi...

Embodiment 3

[0064] The effervescent facial mask is made according to the ratio of the ingredients in the prescription 3 in Example 2, and wet granulation is used to make a soft material that is loose, soft, sticky and suitable for humidity. The soft material is passed through 16 mesh, 20 mesh, 40-mesh sieve, put it in a normal pressure box and dry at 40±5°C for 1 hour, add 8.25g of citric acid and 13.75g of sodium bicarbonate, pass through 20-mesh sieve, 40-mesh sieve and 60-mesh sieve for granulation to obtain uniform size The granules were mixed with an appropriate amount of talcum powder, and compressed with a single-punch tablet machine to obtain three batches of effervescent facial masks. The hardness, disintegration time limit and dissolution rate were measured respectively. The results are shown in Table 4.

[0065] Table 4 Effects of Different Particle Sizes on Effervescent Mask Hardness, Disintegration Time Limit and Dissolution Rate

[0066]

[0067]

[0068] As shown in T...

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Abstract

The invention relates to a whitening effervescent mask using radix angelicae as a main drug and a preparation method thereof. The mask contains the following substances: radix angelicae powder, bletilla striata powder, liposome containing radix angelicae and radix ampelopsis extracts, an effervescent framework material HPMC, starch, sodium bicarbonate, citric acid and talcum powder. The preparation method comprises the following steps: adopting a high-pressure homogenizer to prepare lipidosome in which the radix angelicae extract with photosensitivity and the radix ampelopsis extract with skin irritation are embedded, and preparing the effervescent tablet by adopting wet granulation and tabletting. When the mask is used, a plurality of effervescent tablets can be selected according to conditions, water is added to dissolve the effervescent tablets into paste, and the paste is smeared on the face or other parts needing whitening to form the mask. The traditional Chinese medicine components of the product can effectively inhibit the activity of tyrosinase in the body and reduce melanin pigmentation, and have a good whitening effect; the solid effervescent tablet is convenient to carry and use, is dissolved in water, is fine and uniform, and has good coating property; the process is simple, low in cost and beneficial to industrial production.

Description

technical field [0001] The invention relates to an effervescent facial mask for whitening with angelica dahurica as the main ingredient and a preparation method thereof, belonging to the technical field of pharmaceutical preparations. Background technique [0002] Asian women prefer the pursuit of skin whitening. Traditional Chinese palace whitening plant prescriptions are extensive and profound. For example, in Sun Simiao’s Qianjinfang, it is recorded that Baizhi is mixed with Chinese herbal medicines such as Chuanqiong, Angelica, and Baifuzi to make a paste. Cleansing the face in the morning can make the color pleasant. This topic has consulted a large number of ancient prescriptions, so Research and develop whitening facial mask effervescent tablet products suitable for modern people that are easy to carry and store, with whitening and moisturizing effects, simple production process, and low cost. At present, most mask products on the market are mainly made of liquid-imp...

Claims

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Application Information

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IPC IPC(8): A61K8/9794A61K8/9789A61K8/14A61K8/02A61Q19/02
CPCA61K8/9794A61K8/9789A61K8/14A61K8/0216A61Q19/02A61K2800/782
Inventor 霍清
Owner 霍清
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