Microfluidic blood type detection chip

Abstract

The invention discloses a microfluidic blood type detection chip. The chip comprises a chip body, and the chip body comprises a positive type blood type identification area which is provided with a first sample injection cavity, a quantitative uniform mixing cavity, a positive type reaction cavity and an air hole; a reverse typing blood type identification area which is provided with a second sample injection cavity, a quantitative separation cavity, a reverse typing reaction cavity and an air hole; a sample is injected into the first sample injection cavity, and the sample and a preset diluent in the first sample injection cavity enter the quantitative uniform mixing cavity through the micro-channel; a sample and a diluent are uniformly mixed in the quantitative uniform mixing cavity and then enter the positive setting reaction cavity to react with a reaction reagent for detection; a sample is injected into the second sample injection cavity and enters the quantitative separation cavity through the micro-channel, the sample is separated in the quantitative separation cavity, and separated plasma enters the reverse typing reaction cavity to react with a reaction reagent for detection. The positive and negative typing blood type identification can be simultaneously carried out, so that the blood type identification result is more accurate.

Description

technical field [0001] The invention relates to the field of microfluidic chips, in particular to a microfluidic blood type detection chip. Background technique [0002] Microfluidic chip is an emerging technology industry. Microfluidic detection chip technology integrates the basic operation units such as sample preparation, reaction, separation, and detection in the process of biological, chemical, and medical analysis into a micron-scale chip, which is automatically completed. the whole process of analysis. It has great potential in the fields of biology, chemistry and medicine. [0003] Blood type is a method of classifying blood, among which the ABO and Rh blood group systems are most closely related to human blood transfusion. ABO blood group system: A blood type system divided according to the presence or absence of specific antigens (agglutinogens) A and B on the surface of red blood cells. The ABO blood group system is the first human blood group system discovere...

AI Technical Summary

Problems solved by technology

[0007] In order to solve the deficiencies in the prior art, the present invention provides a microfluidic blood type detection chip to overcome the defects of the existing blood type detection technology, simple operation, small sample usage, automatic detection, positive and negative blood type identification at the same time, The cost is lower, the test results are more accurate, and the hematocrit can be directly detected while performing blood type identification, providing an important basis for blood matching

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