Traditional Chinese medicine composition for infectious disease rehabilitation and application thereof

A technology of composition and traditional Chinese medicine, applied in the direction of anti-infective drugs, drug combinations, antiviral agents, etc., can solve the problems of preventing, treating or alleviating the unsatisfied problems of Chinese medicine compositions and Chinese medicine preparations, so as to enhance the body's immunity and strengthen organs The effect of protection

Active Publication Date: 2021-11-09
TIANJIN UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Therefore, there is an unmet need for Chinese medicine compositions and Chinese medicine preparations suitable for preventing, treating or allevia

Method used

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  • Traditional Chinese medicine composition for infectious disease rehabilitation and application thereof
  • Traditional Chinese medicine composition for infectious disease rehabilitation and application thereof
  • Traditional Chinese medicine composition for infectious disease rehabilitation and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0183] Embodiment 1: the preparation of Chinese medicine composition (granule) of the present invention

[0184] Recipe composition:

[0185] 3 grams of ginseng, 6 grams of Ophiopogon japonicus, 3 grams of schisandra, 8 grams of Poria cocos, 8 grams of Qing Pinellia, 6 grams of Scrophulariaceae, 5 grams of bran-fried atractylodes, 6 grams of tangerine peel, 3 grams of licorice, 6 grams of Bupleurum, and 3 grams of Cimicifuga 10 grams of coix seed, 10 grams of skullcap, 10 grams of verbena, 15 grams of reed root and 2 grams of light bamboo leaves.

[0186] Each of the above Chinese herbal medicines was purchased from the market. Referring to the TLC identification methods under the above-mentioned Chinese medicinal materials listed in the 2020 edition of the "Chinese Pharmacopoeia", a TLC identification study was carried out on each of the Chinese medicinal materials, and the results showed that all the Chinese medicinal materials were qualified.

[0187] Preparation:

[018...

Embodiment 2

[0189] Example 2: Experimental Research on Antioxidant / Anti-inflammatory Pharmacodynamics of Traditional Chinese Medicine Composition of the Present Invention

[0190] In this experiment, based on the luciferase reporter gene system of ARE and NF-κB, the effect of the Chinese medicine composition of the present invention on the activities of ARE and NF-κB was investigated, and the antioxidant and anti-inflammatory effects of the Chinese medicine composition of the present invention were discussed.

[0191] 1 Materials and methods

[0192] 1.1 Experimental Instruments

[0193]

[0194] 1.2 Experimental reagents

[0195]

[0196] 1.3 Experimental drugs

[0197] The Chinese medicine composition (granule) of the present invention prepared according to the method for embodiment 1.

[0198] 1.4 Positive drugs

[0199] Dexamethasone, MedChemExpress. Batch number: HY-14648, within the validity period. Specification: 500mg, usage and dosage: according to clinical usage, it ...

Embodiment 3

[0264] Embodiment 3: The traditional Chinese medicine composition of the present invention is to the RAW264.7 induced by LPS

[0265] Study on the role of expression of inflammatory factors in cells

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PUM

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Abstract

The invention relates to a traditional Chinese medicine composition for infectious disease rehabilitation and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition comprises physically-processed products or active extracts of traditional Chinese medicinal materials including radix ginseng, radix ophiopogonis, fructus schizandrae, poria cocos, rhizoma pinelliae preparata, radix scrophulariae, bran-fried rhizoma atractylodis, pericarpium citri reticulatae, radix glycyrrhizae, bupleurum chinense, rhizoma cimicifugae, semen coicis, radix scutellariae, herba verbenae, rhizoma phragmitis and herba lophatheri; and the traditional Chinese medicine composition can also comprise pharmaceutically-acceptable auxiliary materials. The traditional Chinese medicine composition disclosed by the invention can be used for preventing, treating or relieving sequelae or complications of infectious diseases or promoting functional rehabilitation of damaged tissues, organs or systems caused by the infectious diseases.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and specifically relates to a traditional Chinese medicine composition and traditional Chinese medicine suitable for effectively preventing, treating or alleviating sequelae or complications of infectious diseases or promoting the recovery of damaged tissues, organs or systems caused by infectious diseases preparation. The present invention also relates to the method for preparing the Chinese medicine composition and Chinese medicine preparation of the present invention, and the Chinese medicine composition and Chinese medicine preparation are used for preventing, treating or alleviating the sequelae or complications of infectious diseases or promoting damage to tissues caused by infectious diseases, Use for restoration of function of an organ or system. Background technique [0002] From the clinical cure of the disease to the complete recovery of the patient's physiological function...

Claims

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Application Information

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IPC IPC(8): A61K36/8994A61P31/00A61P31/14A61P39/00A61P39/06
CPCA61K36/258A61K36/8968A61K36/79A61K36/57A61K36/076A61K36/8888A61K36/808A61K36/284A61K36/752A61K36/484A61K36/233A61K36/71A61K36/8994A61K36/539A61K36/85A61K36/899A61P31/00A61P31/14A61P39/06A61P39/00A61K2300/00
Inventor 张伯礼张俊华刘清泉杨丰文黄明郭永明宋新波张晗王跃飞常艳旭刘二伟郑文科
Owner TIANJIN UNIV OF TRADITIONAL CHINESE MEDICINE
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