Grid-shaped detection plate for matrix measurement of magnetic nanoparticle imaging system and measurement method

Abstract

The invention belongs to the technical field of system matrix measurement in magnetic nanoparticle imaging, particularly relates to a grid-shaped detection plate for matrix measurement of magnetic nanoparticle imaging system and a measurement method, and aims to solve the problem that a system matrix in magnetic nanoparticle imaging cannot be simply and quickly measured in the prior art. The method comprises the following steps: adjusting an isolation plate according to the resolution of the magnetic nanoparticle imaging system; obtaining a set number of grid-shaped detection plates formed by concave square crystal lattices arranged in a grid shape; based on the characteristics of the system matrix and the relationship between the system matrix and the voltage signal in the induction coil, gradually increasing the measurement range increased through the detection plate; and splicing the column values corresponding to the square lattices of the detection plate according to the positions of the lattices to obtain a final magnetic nanoparticle imaging system matrix. According to the invention, rapid measurement and calibration of the magnetic nanoparticle imaging system matrix are realized, the resolution ratio is flexible and adjustable, the grid-shaped detection plate is adaptive to various magnetic nanoparticle imaging systems, the cost is reduced, and the efficiency is improved.

Description

technical field [0001] The invention belongs to the technical field of system matrix measurement in magnetic nanoparticle imaging equipment, and in particular relates to a grid-shaped detection plate and a measurement method for matrix measurement of a magnetic nanoparticle imaging system. Background technique [0002] In clinical diagnosis and detection, how to accurately and objectively locate tumors and other lesions has always been an international research hotspot and challenging issue. Existing medical imaging technologies such as CT, MRI, SPECT and other methods all have problems such as high harm, poor positioning, and low precision. In recent years, a new tracer-based imaging method—Magnetic Nanoparticle Imaging (MPI, Magnetic Particle Imaging) technology has been proposed. The technique enables precise localization of imaging targets by detecting the spatial concentration distribution of superparamagnetic iron oxide nanoparticles (SPIONs). Compared with tradition...

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Problems solved by technology

[0005] In order to solve the above-mentioned problems in the prior art, that is, the prior art cannot simply and quickly measure the system matrix in the magnetic nanoparticle imaging equipment, the present invention provides a grid-shaped detection plate for the matrix measurement of the magnetic nanoparticle imaging system , the grid-shaped detection board includes:

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