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Traditional Chinese medicine active component composition for treating cough and preparation method thereof

A technology for active ingredients and compositions, which is applied in the field of active ingredient compositions of traditional Chinese medicines for treating cough and their preparation fields, can solve problems such as the decline of immune system function, and achieve the effects of clear medicinal material basis, clear structure and controllable quality.

Pending Publication Date: 2021-08-03
HETIAN UYGHUR PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The extensive use of antibiotics has led to the rapid formation of drug resistance of pathogens, which leads to the decline of the immune system function of the body.

Method used

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  • Traditional Chinese medicine active component composition for treating cough and preparation method thereof
  • Traditional Chinese medicine active component composition for treating cough and preparation method thereof
  • Traditional Chinese medicine active component composition for treating cough and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0069] Weigh 10mg of Potentateic acid, 10mg of α-cedrol, 10mg of β-sitosterol, 15mg of ammonium glycyrrhizinate, the total weight is 45mg, grind them into powder and mix, dissolve in 10ml of filtered pure water, and then add One of the DMSO was vortexed for 3 minutes to completely dissolve the mixture to obtain the composition of the present invention.

Embodiment 2

[0071]The composition is prepared from the following ingredients: 15 g of poliophyllic acid, 10 g of α-cedrol, 10 g of β-sitosterol, and 15 g of ammonium glycyrrhizinate.

[0072] The above components are taken, added with excipients or carriers, and can be obtained according to the existing granule preparation method.

[0073] This composition granule can adopt following existing method to make:

[0074] Weigh the raw materials of the above composition, grind them into powder and mix them evenly, then add maltodextrin, microcrystalline cellulose, and talcum powder in an appropriate amount to obtain a mixed powder, and then add starch slurry with a volume fraction of 5% to the mixed powder to make a soft material , and sieve the soft materials to obtain wet granules, and finally dry the wet granules to obtain granules of the composition.

Embodiment 3

[0076] The active ingredient composition tablet of the traditional Chinese medicine is prepared from the following ingredients: 30 g of policinic acid, 20 g of α-cedrol, 20 g of β-sitosterol, and 25 g of ammonium glycyrrhizinate.

[0077] Take the above components, add carriers or excipients with reference to Example 2, wet granulate and then compress and coat the tablets to obtain the composition tablets.

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Abstract

The invention belongs to the technical field of traditional Chinese medicines, and discloses a traditional Chinese medicine active component composition for treating cough and a preparation method thereof, the traditional Chinese medicine active component composition for treating cough comprises the following components by mass: 15-35 parts of tormentic acid, 15-25 parts of alpha-cedrol, 15-40 parts of beta-sitosterol, and 18-25 parts of ammonium glycyrrhizinate. The traditional Chinese medicine active component composition for treating cough provided by the invention is clear in pharmacodynamic material basis, is prepared by compatibility of tormentic acid, alpha-cedrol, beta-sitosterol and ammonium glycyrrhizinate, is clear in structure, fixed in component and controllable in quality, and lays a foundation for safety and effectiveness of the traditional Chinese medicine active ingredient composition; the action mechanism is clear, and by adopting a mode of combining classical pharmacology and systematic biological research, the stimulation to the cough center is reduced, so that the purpose of relieving cough is achieved; the composition disclosed by the invention can be used for improving the disorder of an antioxidant balance system in a body, effectively removing excessive free radicals in the body and relieving oxidative damage.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a composition of active ingredients of traditional Chinese medicine for treating cough and a preparation method thereof. Background technique [0002] At present, cough is a common respiratory symptom caused by inflammation, foreign body, physical or chemical stimulation of the trachea, bronchial mucosa or pleura, and has a protective effect of removing foreign bodies and secretions in the respiratory tract. "Hejian Six Books Cough Theory" states: "The six qi of cold, heat, dryness, dampness, wind, and fire all make people cough.". The symptoms of different cough causes are also different. Common coughs are divided into persistent cough, spasmodic cough, dry cough, wet cough, allergic cough, and allergic cough. [0003] The main references for the diagnosis of cough: (1) main clinical symptoms are cough with vocal or sputum; (2) acute cough, the ...

Claims

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Application Information

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IPC IPC(8): A61K31/56A61K31/045A61K31/575C07J63/00C07J9/00C07H15/256C07H1/08C07C35/37C07C29/74C07C29/84C07C29/78A61K9/08A61K9/16A61K9/20A61K9/28A61P11/14A61P11/00A61P11/06A61P29/00A61P39/06
CPCA61K31/56A61K31/045A61K31/575C07J63/008C07J9/00C07H15/256C07H1/08C07C35/37C07C29/74C07C29/84C07C29/78A61K9/08A61K9/1652A61K9/28A61K9/20A61P11/14A61P11/00A61P11/06A61P29/00A61P39/06C07B2200/07C07C2603/96A61K2300/00
Inventor 庞克坚吴志豪
Owner HETIAN UYGHUR PHARMA
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