PIE controller circuit of time-of-flight nucleic acid mass spectrometer and control method thereof

Abstract

The invention discloses a PIE controller circuit of a time-of-flight nucleic acid mass spectrometer and a control method of the PIE controller circuit. The PIE controller circuit comprises a DC power supply module, an LDO voltage stabilization chip, an FPGA time delay module, a logic device, an optical coupling isolation control circuit and an MOSFET cascade control module, and the above circuit units are sequentially connected in the transmission direction from the DC power supply module to the MOSFET cascade control module. The circuit further comprises a trigger signal shaping circuit, a phase inverter and a monostable timer circuit. The LDO voltage stabilizing chip supplies power to the trigger signal shaping circuit, the phase inverter and the monostable timer circuit. According to the PIE controller circuit of the time-of-flight nucleic acid mass spectrometer, the same ions formed at different times are placed on a same starting line through the PIE controller, and a 3KV delay voltage is generated through the controller, so that the ion interval of the ions with different masses is enlarged under the renting of an electric field, and the resolution of mass spectrometry is ensured.

Description

Technical field: [0001] The invention relates to the field of molecular diagnostic nucleic acid mass spectrometry, in particular, the invention relates to a PIE controller circuit of a time-of-flight nucleic acid mass spectrometer and a control method thereof. Background technique: [0002] The existing time-of-flight nucleic acid mass spectrometer technical scheme uses the internal trigger signal of the laser to the delay module, and controls the analog-to-digital converter and the high-voltage pulse module to achieve the purpose of ion delay and improve the resolution of mass analysis, but the output of the laser The external interrupt signal is not very good, there are vibrations, deformities, etc. When the capture circuit and expansion circuit are required to capture and expand, it is easy to be interfered by the outside and cause functional failure; and the laser synchronization signal is captured through the MCU. The counting delay is output to the high-voltage pulse m...

AI Technical Summary

Problems solved by technology

[0002] The existing time-of-flight nucleic acid mass spectrometer technical scheme uses the internal trigger signal of the laser to the delay module, and controls the analog-to-digital converter and the high-voltage pulse module to achieve the purpose of ion delay and improve the resolution of mass analysis, but the output of the laser The external interrupt signal is not very good, there are vibrations, deformities, etc. When the capture circuit and expansion circuit are required to capture and expand, it is easy to be interfered by the outside and cause functional failure; and the laser synchronization signal is captured through the MCU. The counting delay is output to the high-voltage pulse module and the acquisition card. The pulse signal is random, so the time error of the MCU to capture the signal is one cycle. To achieve stability, it needs to be stable within +-200ps, and it is difficult to capture the signal. Finally, it is The existing technical solutions only use a monostable or timer circuit to do a simple delay, or use a delay chip and MCU to control more complex and low precision

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