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Polycinnamic alcohol urea cream and preparation method thereof

A technology of lauryl alcohol and ointment, which is used in ointment delivery, pharmaceutical formulation, emulsion delivery, etc.

Inactive Publication Date: 2021-04-02
XIAMEN ENCHENG PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

The composition and dosage of the main ingredients, the composition of excipients and the function of the product in this patent are quite different from this product

Method used

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  • Polycinnamic alcohol urea cream and preparation method thereof
  • Polycinnamic alcohol urea cream and preparation method thereof
  • Polycinnamic alcohol urea cream and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Except that the dosage of carbomer is 0.5%, the dosage of other raw and auxiliary materials in the prescription is the same as the preliminarily determined prescription.

Embodiment 2

[0031] The dosage of carbomer is 1.0%, and the dosage of other prescription raw materials is the same as the preliminarily determined prescription.

Embodiment 3

[0033] Except that the dosage of carbomer is 1.3%, the dosage of other prescription raw materials is the same as the preliminarily determined prescription.

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PUM

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Abstract

The invention provides a lauromacrogol urea cream and a preparation method thereof. The cream is prepared from lauromacrogol, urea, carbomer, glycerol, benzyl alcohol, tromethamine, dimethicone, phenyl polydimethylsiloxane, liquid paraffin, cetyl palmitate, stearic acid, octyldodecanol, polysorbate 80 and purified water. In the prescription, the dosage of octyldodecanol is 5-15% (W / W), the dosageof carbomer is 0.5-1.5% (W / W), and the swelling speed of aqueous phase solution of carbomer and tromethamine is higher. The lauromacrogol urea cream has the beneficial effects that the swelling speedand effect of carbomer are better, and the production time and cost are saved; and octyldodecanol and carbomer are key auxiliary materials influencing the curative effect of the product, and the clinical curative effect of the product can be guaranteed by controlling the dosage of octyldodecanol and carbomer.

Description

technical field [0001] The invention relates to a lauryl alcohol urea cream and a preparation method thereof. Background technique [0002] Lauromacrogol Urea Cream is used to treat itching, eczema, dermatitis, and ichthyosis requiring antipruritic and moisturizing treatments. It can also be used in the ongoing treatment and follow-up treatment of these skin diseases. Containing lauromacrogol 3.0% (W / W) and urea 5.0% (W / W) in every 1g cream. The product has definite curative effect and good safety, and can be sold in supermarkets, gas stations and other places as a common drug. There is no similar product on the market in China. [0003] Eczema, dermatitis, and scaly disease are common skin diseases, and the most prominent symptom of these diseases is itching. The incidence of eczema is the highest, accounting for 20% of outpatient visits in dermatology, and the incidence of infant eczema accounts for more than 70%. Eczema can significantly affect patients' study, work a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/765A61K31/17A61K9/06A61K47/10A61K47/32A61K47/18A61P17/04A61P17/00A61P37/08A61P29/00
CPCA61K9/0014A61K9/06A61K31/17A61K31/765A61K47/10A61K47/18A61K47/32A61P17/00A61P17/04A61P29/00A61P37/08A61K2300/00
Inventor 王立兴朱国理王斌乐云峰林亚玲
Owner XIAMEN ENCHENG PHARMA CO LTD
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