Povidone-iodine solution with enhanced stability and preparation method thereof
A technology of povidone-iodine and solution, applied in the field of medicine, can solve the problems of not examining the influence of preparation stability, and the effect of stability is not obvious, and achieve the effect of maintaining bactericidal efficacy and ensuring stability
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Embodiment 1
[0024] Embodiment 1: the preparation of the povidone-iodine solution that stability strengthens
[0025] The povidone iodine solution with enhanced stability in this example is made from the following raw materials: povidone iodine 10g, sodium dihydrogen phosphate 4g, disodium hydrogen phosphate dodecahydrate 0.9g, potassium iodate 0.5g, dodeca Add 5 g of sodium alkyl sulfate, adjust the pH to 5.3 with sodium hydroxide, and add purified water to 1000 mL.
[0026] Its preparation method is carried out according to the following steps:
[0027] (1) Take each raw material according to the following weights:
[0028] Povidone iodine 10g, sodium dihydrogen phosphate 4g, disodium hydrogen phosphate dodecahydrate 0.9g, potassium iodate 0.5g, sodium lauryl sulfate 5g;
[0029] (2) Preparation of solution 1: Add the weighed sodium dihydrogen phosphate, disodium hydrogen phosphate dodecahydrate, and potassium iodate into purified water to dissolve it, and it is solution 1;
[0030] (...
Embodiment 2
[0033] Embodiment 2: the preparation of the povidone-iodine solution that stability strengthens
[0034] The povidone iodine solution with enhanced stability in this example is made from the following raw materials: 5 g of povidone iodine, 2 g of sodium dihydrogen phosphate, 1.5 g of disodium hydrogen phosphate dodecahydrate, 0.3 g of potassium iodate, Add 2.5 g of sodium alkyl sulfate, adjust the pH to 5.2 with sodium hydroxide, and add purified water to 1000 mL.
[0035] Its preparation method is carried out according to the following steps:
[0036] (1) Take each raw material according to the following weights:
[0037] Povidone iodine 5g, sodium dihydrogen phosphate 2g, disodium hydrogen phosphate dodecahydrate 1.5g, potassium iodate 0.3g, sodium lauryl sulfate 2.5g;
[0038] (2) Preparation of solution 1: Add the weighed sodium dihydrogen phosphate, disodium hydrogen phosphate dodecahydrate, and potassium iodate into purified water to dissolve it, and it is solution 1; ...
Embodiment 3
[0042] Embodiment 3: the preparation of the povidone-iodine solution of stability enhancement
[0043] The povidone-iodine solution with enhanced stability in this example is made from the following raw materials: povidone-iodine 15g, sodium dihydrogen phosphate 6g, disodium hydrogen phosphate dodecahydrate 2.0g, potassium iodate 1.0g, dodeca Alkyl sodium sulfate 8.5g, sodium hydroxide to adjust pH5.25, purified water was added to 1000mL.
[0044] Its preparation method is carried out according to the following steps:
[0045] (1) Take each raw material according to the following weights:
[0046] Povidone iodine 15g, sodium dihydrogen phosphate 6g, disodium hydrogen phosphate dodecahydrate 2.0g, potassium iodate 1.0g, sodium lauryl sulfate 8.5g;
[0047] (2) Preparation of solution 1: Add the weighed sodium dihydrogen phosphate, disodium hydrogen phosphate dodecahydrate, and potassium iodate into purified water to dissolve it, and it is solution 1;
[0048](3) Preparation ...
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