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Pharmaceutical composition for treating xerophthalmia and asthenopia, preparation method thereof and application of pharmaceutical composition

A technology of composition and visual fatigue, which is applied in the direction of drug combination, drug delivery, and pharmaceutical formulation, etc., can solve the problems of lack of drug composition, achieve the effect of accelerating blood circulation, good safety and economic benefits, and promoting telangiectasia

Inactive Publication Date: 2020-12-29
TEACHING HOSPITAL OF CHENGDU UNIV OF T C M
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] There is a lack of a pharmaceutical composition for dry eye syndrome and visual fatigue, especially an external preparation for smoked eyes

Method used

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  • Pharmaceutical composition for treating xerophthalmia and asthenopia, preparation method thereof and application of pharmaceutical composition
  • Pharmaceutical composition for treating xerophthalmia and asthenopia, preparation method thereof and application of pharmaceutical composition
  • Pharmaceutical composition for treating xerophthalmia and asthenopia, preparation method thereof and application of pharmaceutical composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Embodiment 1, the preparation of pharmaceutical composition of the present invention

[0028] 1. Prescription of raw materials: Pueraria 12g, Radix Paeoniae Alba 15g, Licorice 3g

[0029] 2. Preparation method: Take pueraria root, white peony root, and licorice, add 8 to 10 times the amount of water and decoct for 0.5 to 1 hour to obtain a medicinal liquid, separate the medicinal liquid from the medicinal residue, concentrate and refine the medicinal liquid, and obtain it by spray drying The extract powder is granulated by dry powder to obtain the pharmaceutical composition (decoction-free granules) of the present invention.

[0030] The method for refining the liquid medicine is a conventional refining method for traditional Chinese medicine, including water extraction and alcohol precipitation, alcohol extraction and water precipitation, adsorption clarification, macroporous adsorption resin adsorption, salting out, dialysis and the like.

Embodiment 2

[0031] Embodiment 2, the preparation of pharmaceutical composition of the present invention

[0032] 1. Prescription of raw materials: Pueraria 12g, Radix Paeoniae Alba 12g, Licorice 3g

[0033] 2, preparation method: with embodiment 1.

Embodiment 3

[0034] Embodiment 3, the preparation of pharmaceutical composition of the present invention

[0035] 1. Prescription of raw materials: 10g of kudzu root, 15g of white peony root, 5g of licorice

[0036] 2, preparation method: with embodiment 1.

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Abstract

The invention provides a pharmaceutical composition for treating xerophthalmia and asthenopia, a preparation method thereof and application of the pharmaceutical composition, and belongs to the fieldof traditional Chinese medicines. The pharmaceutical composition is a preparation prepared from the following active pharmaceutical ingredients in weight ratio: 10-15 parts of radix puerariae, 10-15 parts of radix paeoniae alba and 3-5 parts of radix glycyrrhizae. According to the pharmaceutical composition provided by the invention, the radix puerariae, the radix paeoniae alba and the radix glycyrrhizae are reasonably combined, so that the asthenopia and the xerophthalmia can be effectively treated. By clinical verifications, the pharmaceutical composition provided by the invention can effectively relieve discomforts of eyes of a patient, including asthenopia, dryness, foreign body sensation, scrub sensation, eyelid heaviness and the like, prolongs break-up time of the tear film of the patient to a certain extent, and can be effectively used for treating video terminal asthenopia, meibomian gland dysfunction or xerophthalmia of middle-aged and elderly people. The pharmaceutical composition has high safety and good economic benefits, and provides a new medicine choice for clinically treating the xerophthalmia and the asthenopia.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a pharmaceutical composition for treating dry eye syndrome and visual fatigue, a preparation method and application thereof. Background technique [0002] With the development of society and the acceleration of the pace of life, dry eye has become a common, frequently-occurring, and refractory disease in ophthalmology. The incidence of dry eye is increasing year by year. It has become a common ocular surface disease in ophthalmology. Patients often have a series of clinical symptoms. The most common symptoms are visual fatigue, foreign body sensation, dryness, burning sensation, and eye swelling. , eye pain, photophobia, redness, etc. Dry eye syndrome is often accompanied by symptoms of visual fatigue, and with the wide application of video display terminals (computers, televisions, mobile phones, game consoles, etc.) in modern society, the incidence of v...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/71A61K36/65A61K9/00A61P27/02
CPCA61K9/0004A61K9/0014A61K9/0048A61K36/484A61K36/488A61K36/65A61K36/71A61K2236/331A61P27/02A61K2300/00
Inventor 李翔万婧雯杨凤姣李运帆易文华
Owner TEACHING HOSPITAL OF CHENGDU UNIV OF T C M
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