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Emulsion with hair growth effect and preparation method thereof

An emulsion and efficacy technology, which is applied in the field of emulsion with hair growth effect and its preparation, can solve the problems of inability to obtain stable complexes, low utilization rate of active ingredients, and difficulty in exerting hair growth effect, so as to inhibit microbial infection of hair follicles and improve scalp itching , improved damage effect

Active Publication Date: 2020-11-27
PROYA COSMETICS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the solubility of each component varies greatly. Ligusticum chuanxiong oil and tocopheryl nicotinate are oil-soluble components, while glucosyl rutin, epigallocatechin gallate glucoside, and diglucosyl gallic acid are water-soluble components. Stable complex cannot be obtained by mixing, and the transdermal absorption is poor when used directly, resulting in low utilization rate of active ingredients and difficulty in exerting hair growth effect

Method used

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  • Emulsion with hair growth effect and preparation method thereof
  • Emulsion with hair growth effect and preparation method thereof
  • Emulsion with hair growth effect and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0058] Embodiment 1: a kind of preparation method of bicontinuous phase liquid crystal emulsion with hair growth effect, adopts the following steps:

[0059] Step 1: Weigh chuanxiong oil, glucosyl rutin, tocopheryl nicotinate, epigallocatechol gallic acid glucoside, and diglucosyl gallic acid in a mass ratio of 3:1:1:0.5:0.5, and mix them as hair growth actives;

[0060] Step 2: Weigh by the following mass ratios: 5% of the hair growth actives obtained in step 1, 30% of PEG-8 glyceryl isostearate, 5% of PEG-7 glycerol cocoate, 1% of cetearyl alcohol, 20% cetyl ethylhexanoate, 8% butanediol, 5% dipropylene glycol, 26% deionized water;

[0061] Step 3: Mix the hair growth actives described in Step 2, PEG-8 glyceryl isostearate, PEG-7 glycerol cocoate, cetearyl alcohol, and cetyl ethylhexanoate evenly, and heat to 60°C, as the initial oil phase; mix butanediol, dipropylene glycol, and deionized water evenly, and heat to 60°C as the initial water phase;

[0062] Step 4. Slowly ...

Embodiment 2

[0065] A preparation method of a bicontinuous phase liquid crystal emulsion with hair growth effect adopts the following steps:

[0066] Step 1: Weigh chuanxiong oil, glucosyl rutin, tocopheryl nicotinate, epigallocatechol gallic acid glucoside, and diglucosyl gallic acid in a mass ratio of 2:1:1:0.3:0.3, and mix them. as hair growth actives;

[0067] Step 2: Weigh by the following mass ratios: 10% of the hair growth actives obtained in step 1, 20% of PEG-8 glycerol isostearate, 20% of PEG-7 glycerol cocoate, 2% of cetearyl alcohol, 18% Cetyl Ethylhexanoate, 3% Butylene Glycol, 6% Glycerin, 21% Deionized Water;

[0068] Step 3: Mix the hair growth actives described in Step 2, PEG-8 glyceryl isostearate, PEG-7 glycerol cocoate, cetearyl alcohol, and cetyl ethylhexanoate evenly, and heat to 70°C, as the initial oil phase; mix butanediol, glycerol, and deionized water uniformly, and heat to 70°C as the initial water phase;

[0069] Step 4. Slowly add dropwise the initial water...

Embodiment 3

[0072] A preparation method of a bicontinuous phase liquid crystal emulsion with hair growth effect adopts the following steps:

[0073] Step 1: Weigh chuanxiong oil, glucosyl rutin, tocopheryl nicotinate, epigallocatechol gallic acid glucoside, and diglucosyl gallic acid in a mass ratio of 6:1:1:0.5:0.5, and mix them as hair growth actives;

[0074] Step 2: Weigh by the following mass ratios: 10% of the hair growth actives obtained in step 1, 5% PEG-8 glyceryl isostearate, 30% PEG-7 glycerol cocoate, 1% cetearyl alcohol, 15% cetyl ethylhexanoate, 5% dipropylene glycol, 4% propylene glycol, 30% deionized water;

[0075] Step 3: Mix the hair growth actives described in Step 2, PEG-8 glyceryl isostearate, PEG-7 glycerol cocoate, cetearyl alcohol, and cetyl ethylhexanoate evenly, and heat to 72°C, as the initial oil phase; mix dipropylene glycol, propylene glycol, and deionized water evenly, and heat to 72°C as the initial water phase;

[0076] Step 4. Slowly add the initial w...

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Abstract

The invention relates to an emulsion with a hair growth effect and a preparation method thereof. The emulsion is characterized by comprising 0.5-10% by mass of hair growth active matter, and the hairgrowth active matter consists of ligusticum wallichii oil, glucosylrutin, tocopherol nicotinate, epigallocatechin gallatyl glucoside and diglucosyl gallic acid according to a mass ratio of (2-6):1:1:(0.1-0.5):(0.1-0.5). The emulsion provided by the invention has the characteristics of good stability, high transdermal absorption rate, good safety and obvious hair growth effect.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to an emulsion with hair growth effect and a preparation method thereof. Background technique [0002] The advancement of science and technology and the development of economy have accelerated the pace of our life. Factors such as increasing competitive pressure, environmental pollution, irregular life, and changes in eating habits have made the rate of hair loss continue to rise, so hair growth products have always had huge demand and development prospects. Seborrheic alopecia is a common disease in dermatology, androgen secretion disorder, excessive sebum secretion, causing blockage of hair follicles, insufficient blood supply to dermal papilla, nutritional deficiencies, metabolic disorders, leading to necrosis of hair follicles, and microbial infection will accelerate the process of hair loss. Among the commercially available hair growth products, hair growth ingredients such ...

Claims

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Application Information

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IPC IPC(8): A61K8/92A61K8/60A61K8/67A61K8/02A61K8/06A61P17/14A61Q7/00
CPCA61K8/922A61K8/602A61K8/678A61K8/0295A61K8/06A61Q7/00A61P17/14A61K2800/5922A61K2800/592
Inventor 李昊李欣航杨盼盼薛绘韩丹吕旭阳蒋丽刚
Owner PROYA COSMETICS
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