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Antibacterial paste for killing or inhibiting helicobacter pylori in oral cavity and preparation method thereof

A Helicobacter pylori, intraoral technology, applied in biochemical equipment and methods, oral care, antibacterial drugs, etc., can solve the problem of unsatisfactory antibacterial and antibacterial effects, and achieve the improvement of gingival swelling, pain and bleeding, promotion of hyperplasia, and strong health. effect of dentin

Pending Publication Date: 2020-09-29
湖南大海医药集团有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, most of the oral care products such as toothpaste, oral antibacterial paste, tooth powder, mouthwash, and tooth gel on the market use synthetic chemical drugs to kill antibacterial ingredients. Long-term use of synthetic antibacterial agents has potential harm to the human body. And safety issues, although there are some oral care products of Chinese herbal medicine on the market, the antibacterial effect is not ideal, let alone the effect of killing Helicobacter pylori

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] In the embodiment of the present invention, the bacteriostatic ointment for killing or inhibiting Helicobacter pylori in the oral cavity includes the following raw materials in parts by mass: 1 part of lysozyme, 0.5 part of lactoferrin, 0.5 part of frankincense extract, 0.5 part of Eclipta chinensis extract 0.5 parts of Bupleurum extract, 0.5 parts of Sophora flavescens extract, 0.5 parts of Banlangen extract, 0.5 parts of Forsythia extract, 0.5 parts of licorice extract, 0.5 parts of Libumin extract, 0.5 parts of Hedyotis diffusa extract 0.5 part of aloe extract, 0.5 part of chrysanthemum extract, 0.5 part of stevia extract, 0.5 part of bletilla striata extract and 0.77 part of aminocaproic acid, and the rest is toothpaste base.

[0027] In an embodiment of the present invention, the toothpaste base includes the following raw materials in parts by mass: 5-25 parts of friction agent, 10 parts of moisturizing agent, 1.5 parts of foaming agent, 0.3 part of thickener, 0.3 p...

Embodiment 2

[0036] In the embodiment of the present invention, the bacteriostatic ointment for killing or inhibiting Helicobacter pylori in the oral cavity includes the following raw materials in parts by mass: 1.2 parts of lysozyme, 0.8 parts of lactoferrin, 0.8 parts of frankincense extract, 0.8 part of Eclipta chinensis extract 0.8 parts of Xiaobupleurum extract, 0.8 parts of Sophora flavescens extract, 0.8 parts of Banlangen extract, 0.8 parts of Forsythia extract, 0.8 parts of licorice extract, 0.8 parts of Libumin extract, 0.8 parts of Hedyotis diffusa extract 0.8 parts, 0.8 parts of aloe extract, 0.8 parts of chrysanthemum extract, 0.8 part of stevia extract, 0.8 part of Bletilla striata extract and 1.2 parts of aminocaproic acid, and the rest are toothpaste bases.

[0037] In an embodiment of the present invention, the toothpaste base includes the following raw materials in parts by mass: 10 parts of friction agent, 15 parts of humectant, 1.7 parts of foaming agent, 6 parts of thic...

Embodiment 3

[0046] In the embodiment of the present invention, the bacteriostatic ointment for killing or inhibiting Helicobacter pylori in the oral cavity includes the following raw materials in parts by mass: 1.3 parts of lysozyme, 1.2 parts of lactoferrin, 1.2 parts of frankincense extract, 1.2 parts of Eclipta chinensis extract 1.2 parts of Xiaobupleurum extract, 1.2 parts of Sophora flavescens extract, 1.2 parts of Banlangen extract, 1.2 parts of Forsythia extract, 1.2 parts of licorice extract, 1.2 parts of Libumin extract, 1.2 parts of Hedyotis diffusa extract 1.2 parts of aloe extract, 1.2 parts of chrysanthemum extract, 1.2 parts of stevia extract, 1.2 parts of Bletilla striata extract and 1.8 parts of aminocaproic acid, and the rest are toothpaste bases.

[0047] In an embodiment of the present invention, the toothpaste base includes the following raw materials in parts by mass: 15 parts of friction agent, 20 parts of moisturizing agent, 2.3 parts of foaming agent, 9 parts of thi...

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PUM

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Abstract

The invention discloses antibacterial paste for killing or inhibiting helicobacter pylori in the oral cavity and a preparation method thereof. The antibacterial paste comprises the following raw materials in parts by mass: 1 to 1.5 parts of lysozyme, 0.5 to 2.5 parts of lactoferrin, 0.5 to 2 parts of frankincense extract, 0.5 to 2 parts of herba ecliptae extract, 0.5 to 2 parts of minor radix buplenri extract, 0.5 to 2 parts of radix sophorae flavescentis extract, 0.5 to 2 parts of radix isatidis extract, 0.5 to 2 parts of fructus forsythiae extract, 0.5 to 2 parts of radix glycyrrhizae extract, 0.5 to 2 parts of radix stemonae extract, 0.5 to 2 parts of herba hedyotis extract, 0.5 to 2 parts of aloe extract, 0.5 to 2 parts of flos chrysanthemi extract, 0.5 to 2 parts of stevia rebaudianaextract, 0.5 to 2 parts of bletilla striata extract, 0.772.30 parts of aminocaproic acid and the balance of a toothpaste matrix. According to the antibacterial paste capable of killing or inhibiting the helicobacter pylori in the oral cavity provided by the invention, the oral antibacterial paste has the strong-effect lysozyme and frankincense oil, and plays a role in strongly killing the helicobacter pylori for dissolving and degrading helicobacter pylori cell membranes and reducing the adhesiveness of the helicobacter pylori cell membranes and oral mucosa.

Description

technical field [0001] The invention relates to the technical field of biochemical industry, in particular to an antibacterial ointment for killing or inhibiting Helicobacter pylori in the oral cavity and a preparation method thereof. Background technique [0002] Helicobacter pylori is a well-recognized pathogenic bacterium and is listed as a primary carcinogen (the highest level, it is determined to be carcinogenic to humans) by the World Health Organization. It is closely related to gastric diseases (gastritis, ulcer, gastric tumor, gastric cancer). Once infected with Helicobacter pylori, the risk of gastric cancer increases multiple times. [0003] How to effectively treat or prevent Helicobacter pylori is of great significance to the prevention and control of gastric cancer. [0004] At present, the prevention and treatment of Helicobacter pylori is a worldwide problem, and the authoritatively recommended therapy (antibiotics + bismuth preparations + acid suppressants...

Claims

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Application Information

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IPC IPC(8): A61K38/47A61K9/06A61P1/02A61P31/02A61P31/04A61P7/04A61P29/00A61K8/66A61K8/64A61K8/9789A61K8/9794A61K8/44A61Q11/00A61Q17/00A61K38/40A61K36/898A61K31/197
CPCA61K38/47A61K38/40A61K36/324A61K36/28A61K36/185A61K36/489A61K36/195A61K36/315A61K36/634A61K36/484A61K36/748A61K36/896A61K36/886A61K36/287A61K36/898A61K31/197A61K9/06A61P1/02A61P31/02A61P31/04A61P7/04A61P29/00C12Y302/01017A61K8/66A61K8/64A61K8/9789A61K8/9794A61K8/44A61Q11/00A61Q17/005A61K2300/00
Inventor 黄广源
Owner 湖南大海医药集团有限公司
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