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Compound amino acid injection for livestock and preparation method thereof

A compound amino acid and injection technology, which can be applied to non-active ingredients medical preparations, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve problems such as low amino acid content, achieve good curative effect, save production costs, reduce The effect of preparation time

Inactive Publication Date: 2020-07-03
HEBEI KEXING PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] The purpose of the present invention is to provide a compound amino acid injection for livestock to solve the problem of low amino acid content in the injection for livestock;

Method used

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  • Compound amino acid injection for livestock and preparation method thereof
  • Compound amino acid injection for livestock and preparation method thereof
  • Compound amino acid injection for livestock and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1～6

[0048] Embodiments 1-6 compound amino acid injection for livestock and preparation method thereof

[0049] Embodiments 1 to 6 are respectively a compound amino acid injection for livestock. The raw materials for making its active ingredients are the same. The difference is that the amount of raw materials used in different embodiments is different. It is calculated in parts by weight. The following table is injected per 1000L Liquid as an example, wherein the consumption of active ingredient raw materials is shown in Table 1:

[0050] Table 1 The dosage ratio list of each active ingredient raw material

[0051]

[0052]

[0053] The following is the preparation method of the animal compound amino acid injection in Example 1, taking 1000L animal compound injection as an example, including the following steps carried out successively:

[0054] Step 1) Prepare base fluid:

[0055] Take 1000L water for injection, boil and sterilize for 40 minutes, and set aside;

[0056] ...

Embodiment 7

[0091] Example 7 Stability Detection of Animal Compound Amino Acid Injection

[0092] In this example, the compound amino acid injection for animals prepared in Example 1 was tested for quality. The specific detection method is as follows:

[0093] The accelerated test is placed under the conditions of temperature 40±2°C and relative humidity 75±5% for 6 months, and samples are taken at the end of the 0th month, 1st month, 2nd month, 3rd month and 6th month during the test period. The quality standards of WS1~(X~324)~2003Z of "Drug Standards of the State Food and Drug Administration" were tested, and the specific test results are shown in Table 4:

[0094] Table 4 Quality inspection results of compound amino acid injection for livestock

[0095]

[0096]

[0097] As can be seen from Table 4, the animal compound amino acid injection prepared in Example 1 is through the accelerated test, and each index has no obvious change, and the sample quality stability is good and h...

Embodiment 8

[0098] Embodiment 8 Stability comparison of animal compound amino acid injection

[0099] According to the quality detection method of Example 7, the compound amino acid injection for livestock prepared in Examples 1 to 6 and the existing compound amino acid injection for livestock were placed for 24 months and compared for quality detection respectively. The specific detection results are as follows :

[0100] Table 5 Comparison results of quality inspection of compound amino acid injection for livestock

[0101]

[0102]

[0103] As can be seen from Table 5, after the existing animal compound amino acid injection was placed for 24 months, the contents of tryptophan, proline, gamma-aminobutyric acid and tyrosine all decreased, while the animal compound injection prepared by the present invention The compound amino acid injection is more stable, and the content changes little. The content of each amino acid in the animal compound amino acid injection prepared in Exampl...

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Abstract

The present invention discloses a compound amino acid injection for livestock, and belongs to the technical field of animal husbandry and veterinary. Effective ingredients of the injection include 18kinds of amino acids and gamma-aminobutyric acid required by the animal body; by adjusting the amount of leucine and using arginine hydrochloride, histidine hydrochloride, lysine hydrochloride and cysteine hydrochloride, the content of the amino acids in the compound amino acid injection for the livestock is increased, so that the injection is more stable, the production cost is reduced, the injection has the better curative effect, and the problem of relatively low amino acid content of an existing compound amino acid injection for the livestock is solved. The invention also discloses a preparation method of the compound amino acid injection for the livestock. The compound amino acid injection for the livestock is prepared by multistep feeding, so that the stability and solubility of tryptophan, tyrosine and the gamma-aminobutyric acid are improved, oxidation is prevented, and the problem that the existing compound amino acid injection for the livestock is low in stability is solved;and the compound amino acid injection for the livestock is suitable for body repair of the livestock in the disease treatment period and the recovery-after-illness period.

Description

technical field [0001] The invention belongs to the technical field of animal husbandry and veterinary medicine, and relates to an animal injection and a preparation method thereof, in particular to an animal compound amino acid injection and a preparation method thereof. Background technique [0002] Currently, glucose injection, sodium chloride injection and glucose sodium chloride injection are mainly used as replenishing fluids for enhancing animal physical fitness. These three injections are mainly used to replenish water and energy, and to regulate the balance of electrolytes in the body, but they cannot improve the nutritional status of the animal body and supplement the amino acids required by the animal body, and thus cannot effectively regulate the feed intake of the animal, especially for the weak, Animals during the disease period need to supplement amino acids to improve nutrition, thereby promoting the recovery of animals. [0003] Generally weak, sick animals...

Claims

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Application Information

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IPC IPC(8): A61K9/08A61K47/18A61K47/02A61K31/198A61K31/4172A61K31/401A61K31/405A61K31/197A61P3/02
CPCA61K9/0019A61K9/08A61K31/197A61K31/198A61K31/401A61K31/405A61K31/4172A61K47/02A61K47/183A61P3/02A61K2300/00
Inventor 陈淑芳李凤英赵素娟郭艳玉李艳王伟光邢江盼
Owner HEBEI KEXING PHARMA
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