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Alcohol effect dispelling and liver protecting composition as well as product

A technology of anti-alcoholic and liver-protecting composition, which is applied in the direction of drug combination, food ingredients containing natural extracts, dairy products, etc., and can solve the problems of nerves, digestive system discomfort, adverse cardiovascular effects of patients, etc.

Inactive Publication Date: 2020-06-09
INNER MONGOLIA YILI INDUSTRIAL GROUP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the common drug for the clinical treatment of acute alcoholism is naloxone, which belongs to the opioid receptor antagonist. Nervous and digestive system discomforts still exist

Method used

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  • Alcohol effect dispelling and liver protecting composition as well as product
  • Alcohol effect dispelling and liver protecting composition as well as product
  • Alcohol effect dispelling and liver protecting composition as well as product

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0083] The preparation of the anti-alcoholic and liver-protecting composition of the embodiment

[0084] raw material:

[0085] Snaketooth grape leaf extract (Jianshixing Biotechnology Research and Development (Shanghai) Co., Ltd., batch number 171115, measured dihydromyricetin content 53.66%);

[0086] Pueraria root extract (Jianshixing Biotechnology Research and Development (Shanghai) Co., Ltd., batch number 180622, the measured puerarin content is 8.3%);

[0087] Hovenia dulcis seed extract (Jianshixing Biotechnology Research and Development (Shanghai) Co., Ltd., batch number 180515, measured dihydromyricetin content 6.5%);

[0088] Mixed probiotic powder (Danisco (China) Investment Co., Ltd.), each gram contains: Lactobacillus acidophilus NCFM, Lactobacillus paracasei Lpc-37, Bifidobacterium lactis Bi-07, Bifidobacterium lactis Bl-04 each 5 ×10 8 CFU, and Bifidobacterium lactis HN019 3×10 9 CFU.

[0089] Preparation: According to the daily dose of 70kg human body, the...

experiment example 1

[0111] Experimental Example 1 Behavioral Observation Experiment

[0112] experimental method:

[0113] After adaptive feeding for 3 days, 80 mice were randomly divided into 4 groups with 20 mice in each group. Food and water were fasted for 12 hours before the experiment. The experimental group was given different doses of anti-alcohol composition (respectively 1 times, 5 times and 10 times the human dose as the low dose, middle dose and high dose of the experiment) with a gavage dose of 2mL / 100g bw, and the control group was given distilled water , record the gavage time. After 30 minutes of administration, each group was fed with 0.19 mL / 10 g body weight of 56% (V / V) Red Star Erguotou, and the behavioral indicators of the mice were observed.

[0114] After the mice were ingested with white wine, they were immediately placed on a vertical metal net, and the climbing time of the mice on the metal net was recorded.

[0115] Continue to observe the activity of the mice, and ...

experiment example 2

[0122] Experimental Example 2 Determination of Ethanol Content

[0123] experimental method:

[0124] After 3 days of adaptive feeding, 40 rats were randomly divided into 4 groups with 10 rats in each group. Fasting 12h before the experiment, deprivation of water. The experimental group was given different doses of anti-alcohol composition with 2mL / 100g bw gavage dose (respectively according to the animal pharmacology experiment drug conversion method, the dose conversion coefficient of 70kg human dose and 200g rat dose is 0.018, 1 times and 5 times the human dose and 10 times as the low dose, middle dose and high dose of the experiment), the control group was given distilled water, and the gavage time was recorded. After 30 minutes, each group was given 56% white wine by gavage with 1.33mL / 100g bw, and the gavage time was recorded. Blood was taken from the inner canthus at four time points of 0.5h, 1.0h, 2.0h and 3.0h after drinking, and the blood alcohol content was detec...

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Abstract

The invention relates to the fields of food and medicines, particularly to an alcohol effect dispelling and liver protecting composition as well as a product, more particularly to an alcohol effect dispelling and liver protecting composition containing a plant extract and probiotics as well as a product containing the alcohol effect dispelling and liver protecting composition (such as food and medicines).

Description

technical field [0001] The invention relates to the fields of food and medicine, in particular to a composition for relieving alcohol and protecting the liver and products containing the composition. Background technique [0002] China's drinking culture has a long history. Drinking can bring pleasure and carry important cultural functions. In addition, moderate drinking also has the effects of promoting blood circulation, dispelling cold, relieving tension and promoting metabolism. However, long-term excessive drinking can cause alcoholic liver disease, mainly manifested as fatty liver, alcoholic hepatitis, liver fibrosis and cirrhosis, and can cause liver cancer in severe cases. Acute alcoholism refers to the neuropsychiatric symptoms of excitement or depression caused by drinking a large amount of high-concentration alcoholic beverages at one time, accompanied by the process of multi-system damage such as the digestive system and cardiovascular system. In severe cases, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/87A61P1/16A61P39/02A23C9/13A23C9/152A23C9/18A23G3/36A23G3/48A23L2/39A23L2/52A23L33/105A23L33/135A61K35/747A61K35/745A23L2/38
CPCA61K36/87A61K36/72A61K36/488A61K35/747A61K35/745A61P1/16A61P39/02A23C9/13A23C9/152A23C9/18A23L2/39A23L2/52A23G3/366A23G3/48A23L33/105A23L33/135A23V2002/00A23C9/127A23G3/36A23G3/364A23L2/38A23L2/84A23L33/14A23L33/175A61K31/185A61K36/064A23V2400/113A23V2400/165A23V2400/531A61K2300/00A23V2200/30A23V2200/3204A23V2250/21A23V2200/334A23V2250/0644A23V2250/76
Inventor 陈醇何剑华彦俊赵子夫冯昊天朱佳陈奕旻
Owner INNER MONGOLIA YILI INDUSTRIAL GROUP CO LTD
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