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Lactic acid bacteria mask capable of inhibiting propionibacterium acnes and preparation method

A technology of Propionibacterium acnes and lactic acid bacteria, which can be used in pharmaceutical formulas, cosmetic preparations, and dressing preparations, etc. It can solve problems such as skin sensitivity, damaged skin barrier, and aggravate skin barrier damage, and achieve skin barrier repair and good health. Stability, the effect of inhibiting Propionibacterium acnes

Inactive Publication Date: 2020-05-29
河北一然生物科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The skin barrier of some acne patients is damaged, and long-term oral or topical antibiotics and other anti-acne drugs tend to aggravate the damage of the skin barrier, resulting in skin sensitivity

Method used

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  • Lactic acid bacteria mask capable of inhibiting propionibacterium acnes and preparation method
  • Lactic acid bacteria mask capable of inhibiting propionibacterium acnes and preparation method
  • Lactic acid bacteria mask capable of inhibiting propionibacterium acnes and preparation method

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Embodiment 1

[0027] This embodiment relates to a lactic acid bacteria mask essence capable of inhibiting Propionibacterium acnes, comprising the following components:

[0028]

[0029]

[0030] In a second aspect, the present invention also relates to a method for preparing the aforementioned lactic acid bacteria mask essence capable of inhibiting Propionibacterium acnes, said method comprising the following steps:

[0031] Step 1, material A: each component in claim 1, except carbomer, hydroxyethyl cellulose and inactivated freeze-dried powder, all the other components are mixed uniformly;

[0032] Step 2, material B: Carbomer and hydroxyethyl cellulose in each component in claim 1 must be dissolved in water respectively, stirred and heated at 80°C to fully dissolve, then aired to room temperature for subsequent use;

[0033] Step 3, material C: fully dissolve the inactivated freeze-dried powder in the components in claim 1 with pure water and stir evenly; step 4, mix material A, ma...

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PUM

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Abstract

The invention provides lactic acid bacteria mask essence capable of inhibiting propionibacterium acnes and a preparation method. The lactic acid bacteria mask essence is prepared from 5 parts of propylene glycol, 2 parts of PEG-40 hydrogenated castor oil, 1.4 parts of sodium hyaluronate, 2 parts of dipotassium glycyrrhetate, 0.2 part of carbomer, 0.1 part of hydroxyethyl cellulose, 0.2 part of chlorphenesin, 0.05 part of pelargonium graveolens oil, 0.2 part of phenoxyethanol, 2.1 parts of triethanolamine, 0.5 part of inulin, 0.84 part of inactivated freeze-dried powder, and the balance of water. For the lactic acid bacteria mask essence capable of removing acnes provided by the invention, the experiment proves that the lactic acid bacteria mask essence has an obvious inhibition effect on propionibacterium acnes, the diameter of an inhibition zone can reach 17.94 mM, meanwhile, the lactic acid bacteria mask essence is not sensitive to temperature and illumination and has good stabilityunder the room temperature condition and natural illumination, and the change of the diameter of the inhibition zone is less than 2mM after the lactic acid bacteria mask essence is stored for two months under the conditions of room temperature and natural illumination.

Description

technical field [0001] The invention relates to the field of biological strains, in particular to a lactic acid bacteria facial mask capable of inhibiting Propionibacterium acnes and a preparation method thereof. Background technique [0002] Acne is a chronic inflammatory skin disease of the pilosebaceous glands, with an incidence rate of 70%-87%, and occurs frequently in adolescence. The clinical manifestations are mainly blackheads, whiteheads, inflammatory papules, and pustules on the face, chest and back. [0003] Propionibacterium acnes overgrowth plays a crucial role in the occurrence of acne. The formation of microcomedone and acne creates a good local environment for the proliferation of Propionibacterium acnes with anaerobic growth characteristics. At present, it is believed that Propionibacterium acnes can participate in the occurrence and development of acne inflammation through innate immunity, acquired immunity and direct induction. The early inflammation of ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/99A61K8/92A61Q19/00A61Q17/00A61P17/10
CPCA61K8/99A61K8/922A61Q17/005A61Q19/00A61P17/10A61K2800/85
Inventor 赵林森贾晓蒙赵永娇路江浩孙新凯刘明月赵星霍文敏杨玲
Owner 河北一然生物科技股份有限公司
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