Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Novel rumen bypass biotin

A biotin and rumen-passing technology, which is applied in the field of new rumen-passing biotin, can solve the problems of less utilization of the small intestine, waste of biotin, failure to add biotin, etc.

Active Publication Date: 2020-05-29
安徽东方天合生物技术有限责任公司
View PDF5 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, it is necessary to add biotin from exogenous sources to meet the needs. However, due to the microbial action of the rumen, if biotin is directly added to the diet, part of it will be degraded in the rumen, and very little can reach the small intestine and be utilized.
This will not only fail to achieve the effect of adding biotin, but also cause waste of biotin

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Novel rumen bypass biotin

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] A kind of rumen biotin, its composition is as follows: ball core, is made up of biotin and PEG4000; The weight ratio of biotin and PEG4000 is 1:0.4; The first coating that covers described ball core; Wherein, said first The coating consists of paraffin wax, lactose, calcium hydrogen phosphate, and calcium phosphate in a weight ratio of 20:10:10:10; the weight ratio of the ball core to the first coating is 50:50.

[0067] In the rumen-passed biotin described in this embodiment, by weight percentage: the content of the pellet core is 50%, and the content of the first coating is 50%.

[0068] This embodiment also provides the preparation method of the rumen-passed biotin, including:

[0069] Put biotin into a pulverizer, pass through a 120-mesh sieve, mix the obtained product with PEG4000 at a ratio of 1:0.4, heat to about 70°C and melt, then cool to obtain a solid dispersion, which is used as a pellet core.

[0070] Pass solid paraffin and lactose through a 50-mesh sieve...

Embodiment 2

[0074] A rumen-passed biotin, the only difference from Example 1 is that the solid paraffin is replaced by an equivalent amount of glyceryl monostearate. The preparation method refers to Example 1.

Embodiment 3

[0076] A rumen-passing biotin, which is composed as follows: a ball core, composed of biotin and PEG4000, wherein the weight ratio of biotin and PEG4000 is 1:0.4; the first coating covering the ball core; wherein, the first A coating is composed of paraffin wax, lactose, calcium hydrogen phosphate, and calcium phosphate in a weight ratio of 10:5:10:10; a second coating covering the first coating; wherein the second coating is paraffin wax ; The weight ratio of the ball core, the first coating, and the second coating is 50:35:15.

[0077] In the rumen-passed biotin described in this embodiment, by weight percentage: the content of the pellet core is 50%, the content of the first coating is 35%, and the content of the second coating is 15%.

[0078] This embodiment also provides the preparation method of the rumen-passed biotin, comprising: preparing pellet cores in the same manner as in Example 1 (the ratio of raw materials is different from that in Example 1), coating the pell...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a novel rumen bypass biotin. The rumen bypass biotin mainly comprises the following raw materials: biotin, polyethylene glycol, an adhesive and an excipient. The rumen bypass biotin in embodiments comprises a pill core and a coating covering the pill core, wherein the pill core contains the biotin and the polyethylene glycol, and the coating comprises the adhesive and the excipient. The novel rumen bypass biotin provided by the embodiments has a low degradation rate in a rumen. By use of the rumen bypass biotin, cows can reach the best production performance and health condition and the earnings of a pasture can be substantially increased.

Description

technical field [0001] The invention relates to a novel rumen-passing biotin and its preparation method and application. Background technique [0002] Biotin is an organic compound necessary for the maintenance of normal functions in the animal body. As a component of enzymes, it participates in the metabolism of the three major nutrients in the body. The traditional view is that biotin in feed and biotin synthesized by rumen and intestinal microorganisms can meet the basic needs of ruminants for biotin. However, in recent years, with the continuous improvement of dairy cow breeds and the improvement of breeding intensification, the demand for biotin is also higher, especially for high-yielding dairy cows. A large number of studies have confirmed that adding biotin to the diet can improve the health and production performance of cattle limbs and hooves, so that dairy cows can achieve the best production performance and health status. Therefore, it is necessary to add bioti...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A23K50/10A23K20/174A23K40/30
CPCA23K50/10A23K20/174A23K40/30
Inventor 李寰旭赵鑫源
Owner 安徽东方天合生物技术有限责任公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com