Application of dehydroevodiamine in preparation of medicine for treating acute gastritis
A technology for dehydroevodiamine and acute gastritis, which is applied to the application field of dehydroevodiamine in the preparation of medicines for treating acute gastritis, can solve problems such as the absence of dehydroevodiamine on acute gastritis and the like, and achieves improvement of SOD level and ulcers. Formation of significant reduction and improvement effects
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[0019] Experimental example 1 : Evaluate the therapeutic effect of the target compound (dehydroevodiamine) on acute gastritis by using the acute gastritis model induced by absolute ethanol in mice:
[0020] 1. Method: After adapting to the environment for 1 week, the mice were randomly divided into 4 experimental groups (control group, model group, evodiamine dosage group and dehydroevodiamine dosage group), each group containing 10 animals, Intragastric administration once a day for three consecutive days. The mice in the control group received 1% CMC (sodium carboxymethyl cellulose); the mice in the model group received 1% CMC; the evodiamine dose group was given 20 mg / kg of evodiamine by intragastric administration, and the dehydroevodiamine dose group was given dehydroevodiamine by intragastric administration. Evodiamine 20mg / kg. Before the experiment, the mice were fasted for 12 hours but had free access to water. Then the mice were treated as above, 0.01ml / g dose of ...
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