Licoflavone-containing toothpaste and preparation method and application thereof

A technology of licorice flavonoids and toothpaste, which is applied in the field of toothpaste containing licorice flavonoids and its preparation, which can solve the problems of poor pertinence of antibacterial active ingredients, reduced self-healing ability of oral tissues, and low content of active ingredients, so as to improve self-healing Ability, improvement of oral restoration ability, less side effects

Pending Publication Date: 2020-02-14
惠州市九惠制药股份有限公司
View PDF5 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In the current traditional Chinese medicine toothpaste on the market, there are too many prescription flavors of traditional Chinese medicine, resulting in a complex composition of ingredients, which makes the content of active ingredients in the toothpaste, which is already limited, e...

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] A toothpaste containing licorice flavonoids, comprising the following components in parts by weight: 45 parts of calcium hydrogen phosphate dihydrate, 3 parts of silicon dioxide hydrate, 2.5 parts of sodium lauryl sulfate, 10 parts of sorbitol, polyethylene glycol 7 parts of diol-400, 5 parts of propylene glycol, 1 part of hydroxyethyl cellulose, 0.3 parts of xanthan gum, 0.15 parts of sodium benzoate, 0.25 parts of sodium pyrotetraphosphate, 1 part of licorice flavonoids, 0.5 parts of glycyrrhizin, magnolia bark 0.1 part of phenol, 0.1 part of paeonol, 0.5 part of peppermint oil, 0.6 part of essence, 1 part of 1% brilliant blue solution, 0.5 part of eugenol and 0.8 part of sodium monofluorophosphate.

[0035] The preparation method of the above-mentioned toothpaste containing licorice flavonoids, the concrete steps are as follows:

[0036] (1) Take hydroxyethyl cellulose and xanthan gum in sorbitol, stir evenly, and obtain intermediate A;

[0037] (2) Separately take so...

Embodiment 2

[0042] A toothpaste containing licorice flavonoids, comprising the following components in parts by weight: 40 parts of calcium hydrogen phosphate dihydrate, 2 parts of silicon dioxide hydrate, 3 parts of sodium lauryl sulfate, 8 parts of sorbitol, polyethylene glycol Glycol-4005 parts, propylene glycol 4 parts, hydroxyethyl cellulose 0.5 parts, xanthan gum 0.2 parts, sodium benzoate 0.10 parts, sodium pyrotetraphosphate 0.15 parts, licorice flavonoids 0.5 parts, glycyrrhizin 0.2 parts, magnolol 0.05 parts, 0.055 parts of paeonol, 0.3 parts of peppermint oil, 0.6 parts of essence, 1 part of 1% brilliant blue solution, 0.4 parts of eugenol and 0.7 parts of sodium monofluorophosphate.

[0043] The preparation method of the above-mentioned toothpaste containing licorice flavonoids, the concrete steps are as follows:

[0044] (1) Take hydroxyethyl cellulose and xanthan gum in sorbitol, stir evenly, and obtain intermediate A;

[0045] (2) Separately take sodium benzoate, sodium py...

Embodiment 3

[0050] A toothpaste containing licorice flavonoids, comprising the following components in parts by weight: 50 parts of calcium hydrogen phosphate dihydrate, 4 parts of silicon dioxide hydrate, 5 parts of sodium lauryl sulfate, 12 parts of sorbitol, polyethylene glycol Glycol-40010 parts, 6 parts of propylene glycol, 1.5 parts of hydroxyethyl cellulose, 0.4 parts of xanthan gum, 0.20 parts of sodium benzoate, 0.30 parts of sodium pyrotetraphosphate, 1.5 parts of licorice flavonoids, 0.6 parts of glycyrrhizin, magnolol 0.15 parts, 0.15 parts of paeonol, 0.6 parts of peppermint oil, 0.8 parts of essence, 1 part of 1% brilliant blue solution, 0.6 parts of eugenol and 0.9 parts of sodium monofluorophosphate.

[0051] The preparation method of the above-mentioned toothpaste containing licorice flavonoids, the concrete steps are as follows:

[0052] (1) Take hydroxyethyl cellulose and xanthan gum in sorbitol, stir evenly, and obtain intermediate A;

[0053] (2) Separately take sodi...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention provides licoflavone-containing toothpaste. The licoflavone-containing toothpaste comprises the following components in parts by weight of 40-50 parts of calcium hydrogenphosphate dihydrate, 2-4 parts of silicon dioxide hydrate, 3-5 parts of sodium dodecylsulfate, 8-12 parts of sorbitol, 5-10 parts of polyethylene glycol-400, 4-6 parts of propylene glycol, 0.5-1.5 parts of hydroxyethyl cellulose, 0.2-0.4 part of xanthan gum, 0.10-0.20 part of sodium benzoate, 0.15-0.30 part of sodium pyrophosphate, 0.5-1.5 parts of licoflavone, 0.2-0.6 part of glycyrrhizin, 0.05-0.15 part of magnolol, 0.05-0.15 part of paeonol, 0.3-0.6 part of peppermint oil, 0.6-0.8 part of essence, 1 part of a 1% brilliant blue solution, 0.4-0.6 part of eugenol and 0.7-0.9 part of sodium monofluorophosphate. The toothpaste uses the licoflavone as a main drug and uses a toothpaste substrate as an auxiliary drug, the formula is scientific and simple, the raw materials are low in cost, and the cost-effectiveness is high. The toothpaste is high in restraining points for pathogenic bacteria, and has favorable efficacy of resisting bacteria, diminishing inflammation and cleaning oral cavity.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine oral care and health care, in particular to a toothpaste containing licorice flavonoids and its preparation method and application. Background technique [0002] Oral ulcer, commonly known as "oral sore", is a common ulcerative injury disease that occurs in the oral mucosa. It is more common in the inner lip, tongue, tongue belly, buccal mucosa, vestibular groove, soft palate and other parts. The mucosa in these parts lacks stratum corneum. or poor keratosis. Tongue ulcers refer to oral ulcers that occur on the tongue and the abdomen of the tongue. When oral ulcers attack, the pain is severe, and the local burning pain is obvious. In severe cases, it will also affect eating and speaking, and cause inconvenience to daily life; it may be accompanied by bad breath, chronic pharyngitis, constipation, headache, dizziness, nausea, fatigue, irritability, fever, and swollen lymph nod...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K8/49A61K8/35A61K8/34A61Q11/00A61P1/02A61P31/02A61P29/00
CPCA61K8/498A61K8/9789A61K8/35A61K8/347A61Q11/00A61P1/02A61P31/02A61P29/00A61K2800/5922
Inventor 刘强黄辉球
Owner 惠州市九惠制药股份有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products