POCT full-automatic chemiluminiscence device based on active magnetic separation technology

Abstract

The invention relates to the field of full-automatic chemiluminescence, especially to a POCT full-automatic chemiluminiscence device based on active magnetic separation technology. The POCT full-automatic chemiluminiscence device comprises a mounting frame, a sample adding arm, a constant-temperature control bin, a TIP head unloading frame and a magnetic separation component are mounted on the mounting frame, the constant-temperature control bin comprises a first reaction bin and a second reaction bin, the magnetic separation component comprises a first magnetic separation component and a second magnetic separation component, the first magnetic separation component is correspondingly arranged above the first reaction bin, and the second magnetic separation component is correspondingly arranged above the second reaction bin. The first reaction bin and the second reaction bin which are independent of each other are adopted, the first reaction bin and the second reaction bin can operate independently, dual-channel detection is achieved, the detection efficiency can be improved, and emergency treatment requirements are met. According to the active magnetic separation technology of themagnetic separation component, magnetic beads are directly attracted to the bottom of a magnetic separation sleeve through cooperation of the disposable magnetic separation sleeve and a magnetic bar,the active magnetic separation effect is achieved, the cleaning efficiency is improved, and the background of the system is reduced.

Description

technical field [0001] This application relates to the field of fully automatic chemiluminescence, in particular to a POCT fully automatic chemiluminescent device based on active magnetic separation technology. Background technique [0002] Fully automatic chemiluminescence is a sub-field of in vitro diagnostics. Due to its high sensitivity, good specificity, high degree of automation, and wide linear range, it has become an absolute mainstream detection method in clinical applications, accounting for 30% of the entire in vitro diagnostic market. above and growing rapidly. Traditional chemiluminescence suppliers such as Roche, Abbott, Siemens, and Beckman are all large-scale chemiluminescence, with a measurement speed ranging from 100T / H to 600T / H, but for a large number of primary hospitals, due to the limited sample size, the use of large instruments is inefficient , the maintenance cost is high, and the reagents are 100 servings / box. After opening the cover, if it cannot...

AI Technical Summary

Problems solved by technology

Traditional chemiluminescence suppliers such as Roche, Abbott, Siemens, and Beckman are all large-scale chemiluminescence, with a measurement speed ranging from 100T / H to 600T / H, but for a large number of primary hospitals, due to the limited sample size, the use of large instruments is inefficient , the maintenance cost is high, and the reagents are 100 servings / box. After opening the cover, if it cannot be used up in a short time, it can only be discarded

The existing POCT is basically based on the principle of chromatography, the detection sensitivity is not high, the precision is not high, and it can only be used for partial immune detection. Some manufacturers have introduced POCT chemiluminescence, but the magnetic separation efficiency is not high, resulting in errors between channels. Larger, and requires manual sample addition, cannot be fully automated, affecting detection efficiency

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