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Seneca Valley virus (SVV)/CH/ZZ/2016

A technology of Seneca, 2016cgmccno.14886, applied in the direction of virus/bacteriophage, virus, antiviral agent, etc., can solve the problems of immeasurable economic loss and insufficient attention

Active Publication Date: 2019-12-10
JINYUBAOLING BIO PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] There are not many research reports on SVV in my country, and there are currently no reports on the research on the physical and chemical properties of the virus. Most farmers have not paid enough attention to the disease, but the disease has formed a global spread trend. Once a large outbreak trend occurs , the economic loss is immeasurable

Method used

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  • Seneca Valley virus (SVV)/CH/ZZ/2016
  • Seneca Valley virus (SVV)/CH/ZZ/2016
  • Seneca Valley virus (SVV)/CH/ZZ/2016

Examples

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Embodiment 1

[0026] Example 1 Identification of physical and chemical properties of Seneca Valley virus SVV / CH / ZZ / 2016CGMCC No.14886

[0027] 1. Materials and primer design

[0028] 1.1 Tissue materials, cells and experimental animals

[0029] Tissue disease material: clinical samples of pigs with suspected SVV disease in a pig farm in Henan.

[0030] Cells: porcine kidney cells (PK-15), purchased from China Veterinary Drug Control Institute, frozen by our laboratory.

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Abstract

The invention discloses a Seneca Valley virus (SVV) / CH / ZZ / 2016 strain with the specific physical and chemical characteristics. The Seneca Valley virus (SVV) / CH / ZZ / 2016 strain is a small non-envelopedRNA virus, and belongs to the small RNA virus family. The virus is resistant to organic solvents, protease and acid, but sensitive to alkali and shows sensitivity to high temperature. The physical andchemical characteristics of the Seneca Valley virus(SVV) / CH / ZZ / 2016 strain are of great significance for the research on how to prevent and control SVV epidemic and SVV vaccine development.

Description

technical field [0001] The present invention relates to Seneca Valley virus, in particular to a Seneca Valley virus SVV / CH / ZZ / 2016 strain with specific physical and chemical properties, wherein the preservation number of the strain is CGMCC No.14886, and the present invention belongs to biomedical technology field. Background technique [0002] Seneca Valley virus (SVV), also known as Seneca virus A (SVA), is a newly discovered non-enveloped small RNA virus in recent years, belonging to the Picornaviridae family, and the only member of the Seneca virus genus , which is the closest to the heart virus, with a diameter of 25-30nm and a regular dodecahedral structure. SVV can cause the death of newborn piglets with porcine vesicular symptoms, clinically its symptoms are difficult to distinguish from foot-and-mouth disease, porcine vesicular disease and vesicular stomatitis (LM Hales, NJ Knowles, et al. Complete genome sequence analysis of Seneca Valley virus-001 , novel oncoly...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12N7/00A61K39/125A61P31/14C12R1/93
CPCC12N7/00A61K39/12A61P31/14C12N2770/32021C12N2770/32034A61K2039/525A61K2039/552
Inventor 张燕红史琳凯齐志涛路荣杜宇荣谢雪岑刘国英魏学峰陈九连范秀丽郝鹏高艳华李雪峰
Owner JINYUBAOLING BIO PHARMA CO LTD
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