Peppermint mouthwash tablet containing artificial saliva and preparation method of peppermint mouthwash tablet
A technology of artificial saliva and mouthwash tablets, applied in the field of oral hygiene products, can solve the problems of insufficient dissolution, affecting cleaning effect, slow dissolution speed, etc., and achieves good oral cleaning and breath freshening effect, fast dissolution speed and low cost. Effect
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Embodiment 1
[0078] The preparation of embodiment 1 mouthwash tablet of the present invention
[0079] a, granulation: by mass percentage, take menthol 10%, chlorogenic acid 30%, artificial saliva 2.5%, citric acid: sodium bicarbonate (0.4:0.5, w:w) 40%, PVPP 6%, wood Sugar alcohol 10%, PEG6000 1.5%, stirring and mixing, 60% ethanol wet granulation, prepared into granules;
[0080] b. Whole-grain tabletting: the granule mixture prepared in step a is placed into a tablet press for tableting to obtain regular and smooth sheet-like products;
[0081] c. Packaging: choose light aluminum-plastic film packaging to make the finished product.
[0082] Take 6 mouthwash tablets (tablet weight 0.5g), test the disintegration time limit in artificial saliva, and all the tablets disintegrate and dissolve within 30s.
Embodiment 2
[0083] The preparation of embodiment 2 mouthwash tablet of the present invention
[0084] In terms of mass percentage, menthol 15%, tea polyphenols 10%, artificial saliva 0.5%, citric acid: sodium bicarbonate (0.4:0.5, w:w) 50%, PVPP 8%, xylitol 15%, PEG6000 1.5%, stirring and mixing, wet granulation with 95% ethanol, prepared into granules, whole granules compressed into tablets, packaged in aluminum-plastic film, and ready to be obtained.
Embodiment 3
[0085] The preparation of embodiment 3 mouthwash tablet of the present invention
[0086] In terms of mass percentage, menthol 5%, tea polyphenols 10%, chlorogenic acid 30%, artificial saliva 1.5%, citric acid: sodium bicarbonate (0.4:0.5, w:w) 30%, PVPP 7%, Xylitol 15%, PEG6000 1.5%, stirring and mixing, 60% ethanol wet granulation, prepared into granules, the whole granules are compressed into tablets, and packaged with aluminum-plastic film.
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