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Natural composition capable of improving blood micro-circulation disturbance and osteoporosis and preparation method thereof

A technology for osteoporosis and blood microcirculation, applied in drug combinations, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve problems such as large adverse reactions, improve transportation and absorption, reduce blood viscosity, improve Effects on Blood Fluidity

Pending Publication Date: 2019-08-09
EZHOU INST OF IND TECH HUAZHONG UNIV OF SCI & TECH +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, the drugs commonly used in the treatment of osteoporosis mainly include bone resorption inhibitors or bone formation accelerators such as estrogen, bisphosphonates, and denosumab. Although they have certain curative effects, they have relatively large adverse reactions.

Method used

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  • Natural composition capable of improving blood micro-circulation disturbance and osteoporosis and preparation method thereof
  • Natural composition capable of improving blood micro-circulation disturbance and osteoporosis and preparation method thereof
  • Natural composition capable of improving blood micro-circulation disturbance and osteoporosis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] This embodiment provides a natural composition that can improve blood microcirculation disorders and osteoporosis. The raw materials include: in weight percent, 20% of Panax notoginseng extract, 15% of peach kernel extract, and Drynaria fortunei extract 5 %, safflower extract 20%, angelica extract 15%, maca extract 15%, and licorice extract 10%.

[0039] The content of panax notoginseng saponins in the panax notoginseng extract is greater than or equal to 100 mg / g, and the preparation method is:

[0040] Take an appropriate amount of dried Panax notoginseng, pulverize, mix with 70% ethanol at a mass-volume ratio of 1:5, soak for 24 hours, extract at 80°C for 4 hours, and concentrate to extract under reduced pressure. The resulting extract is dried in a drying oven, that is Get Panax notoginseng extract.

[0041] The content of amygdalin in the peach kernel extract is ≥200mg / g, and the preparation method is:

[0042] Take an appropriate amount of peach kernels, pulverize, mix w...

Embodiment 2

[0055] This embodiment provides a natural composition that can improve blood microcirculation disorders and osteoporosis. The raw materials include: in weight percentage, 20% of Panax notoginseng extract, 20% of peach kernel extract, and 10% of Drynaria fortunei extract. %, safflower extract 15%, angelica extract 10%, maca extract 20%, and licorice extract 5%. The preparation method is basically the same as in Example 1.

Embodiment 3

[0057] This embodiment provides a natural composition that can improve blood microcirculation disorders and osteoporosis. The raw materials include: 15% of Panax notoginseng extract, 10% of peach kernel extract, and 15% of Drynaria fortunei extract in weight percentage. %, safflower extract 20%, angelica extract 15%, maca extract 10%, and licorice extract 15%. The preparation method is basically the same as in Example 1.

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Abstract

The invention provides a natural composition capable of improving blood micro-circulation disturbance and osteoporosis and a preparation method thereof. The natural composition is prepared from 10-20parts of a radix notoginseng extractive, 10-20 parts of a peach kernel extractive, 5-15 parts of a rhizoma drynariae extractive, 10-20 parts of a safflower extractive, 10-20 parts of an extractive from Angelica sinensis, 10-20 parts of a maca extractive and 5-15 parts of a licorice root extractive. The pharmaceutical composition contains various effective ingredients, for the synergic effect of different targets and information accesses, the effective ingredients are matched, blood vessels are expanded, blood viscosity is lowered, the blood flowability is improved, the blood microcirculation disturbance is improved, transportation and absorption of calcium, oxygen and other nutrients are promoted so as to improve the metabolic disorder states of osteoblasts and osteoclast, the bone mineraldensity, the bone calcium, the bone phosphate and the bone mineral content are increased, and the effect of treating osteoporosis is achieved. The composition adopts natural medicinal materials as raw materials, the multi-ingredient and multi-target synergic effect is achieved, both symptoms and root causes are addressed, and no toxic or side effect is caused.

Description

Technical field [0001] The invention belongs to the technical field of natural compositions, and specifically relates to a natural composition for improving blood microcirculation disorders and ameliorating osteoporosis and a preparation method thereof. Background technique [0002] Osteoporosis (OP) is a systemic bone metabolism disease that can occur at any age, but it is more common in postmenopausal women and elderly men. It is mainly characterized by low bone mass and damage to the microstructure of bone tissue. Increased fragility and easy fracture. Osteoporotic fractures are extremely harmful and are one of the main causes of disability and death in elderly patients. Within 1 year after a hip fracture occurs, 20% of patients will die of various complications, and about 50% of patients will become disabled and their quality of life will be significantly reduced. The treatment and care of osteoporosis and fractures require a lot of manpower, material resources and financia...

Claims

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Application Information

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IPC IPC(8): A61K36/736A61P19/10A61P9/00
CPCA61K36/126A61K36/232A61K36/258A61K36/286A61K36/31A61K36/484A61K36/736A61K2236/33A61K2236/331A61K2236/333A61K2236/51A61K2236/53A61P9/00A61P19/10A61K2300/00
Inventor 余龙江刘浩陈晶晶李东张稀雯金文闻
Owner EZHOU INST OF IND TECH HUAZHONG UNIV OF SCI & TECH
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