Use of chlorophyll derivatives to improve muscle microcirculation disorder
A technology of microcirculation disorder and chlorophyll, which is applied in the field of medicine, can solve problems such as easy stomach discomfort, high drug prices, and limited use of people, so as to prevent and improve muscle microcirculation disorders, and is applicable to a wide range of people. safe effect
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
preparation example Construction
[0051] Preparation of reference solution: Accurately weigh 0.143g of spectrally pure ferric oxide dried at 130°C to constant weight, put it in a beaker, add 5ml of hydrochloric acid solution (1→2) to dissolve, transfer to a 100ml measuring bottle, add Add 4ml of hydrochloric acid solution (1→2), add water to the mark, shake well, accurately measure 10ml, put it in a 100ml measuring bottle, add water to the mark, shake well to get a solution containing about 100μg of Fe per 1ml. Accurately measure 0, 0.2, 0.4, 0.6, 0.8 and 1.0ml of the above solutions respectively, put them in a 10ml measuring bottle, add nitric acid solution (1→500) to the mark, shake well, and you get it.
[0052] Preparation of the test solution: Take an appropriate amount of sample, grind it finely, accurately weigh 10mg, put it in a 50ml beaker, add 1.5ml of nitric acid, 3 drops of perchloric acid, cover with a watch glass, heat to nearly dry at 150-160°C, add Nitric acid (1→2) 2ml, cover with a watch glas...
Embodiment 1
[0086] Example 1 The protective effect of silkworm excrement extract on muscle acute microcirculation disturbance
[0087] According to the above-mentioned method, the iron chlorophyllin sodium weight percentage content is about 37.6%, and other chlorophyll derivatives are calculated as iron chlorophyllin (b) for more than 60.0% of the silkworm excrement, for its effect on rabbit muscle acute microcirculation disorder The role of the test, the results are as follows.
[0088] Table 1 The effect of silkworm excrement extract on the change rate of rabbit muscle microcirculation ( n=6)
[0089]
[0090] Note: Compared with the negative control group: *: P<0.05, **: P<0.01
[0091] Table 1 shows that, compared with the negative control group, the change rate of blood perfusion (PU) in the high and middle dose groups of silkworm excrement extract was significantly reduced (P<0.01); The rate of change was significantly reduced (P<0.01). The change rate of blood cell velocity...
Embodiment 2
[0092] Example 2 The protective effect of silkworm excrement extract on acute microcirculation disturbance
[0093] Repeat the experiment of Example 1, the difference is that the iron chlorophyllin sodium iron chlorophyllate content is about 29.1% by weight, and other chlorophyll derivatives are tested with iron chlorophyllin (b) above 60.0% silkworm excrement. The results showed that blood perfusion (PU), blood cell aggregation (CMBC) and movement blood cell velocity (V) rate of change in the high, middle and low dose groups all decreased, indicating that the muscle microcirculation disorder of the tested rabbits was improved.
[0094] It can be known from the above examples that sodium ferric chlorophyllin and chlorophyll derivatives containing sodium ferric chlorophyllin (such as silkworm excrement) can effectively improve or regulate blood perfusion, concentration of moving blood cells and speed of moving blood cells, thereby improving muscle Acute microcirculation disorder,...
PUM
Property | Measurement | Unit |
---|---|---|
relative humidity | aaaaa | aaaaa |
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com