Composition containing withaferin A and application of composition

Abstract

The invention provides a composition containing withaferin A, and relates to the technical field of medicines. The composition comprises topiramate and the withaferin A in a mass ratio of (1-25)*10<3>:1. Through the combined application of the topiramate and the withaferin A, the using amount of the topiramate and the withaferin A can be reduced, the side effects of the topiramate and the withaferin A can be obviously reduced, and the effects of reducing the body weight, improving the insulin sensitivity and optimizing the lipid metabolism more significantly can be achieved. The composition can still achieve the effects of significantly reducing the body weight, improving the insulin sensitivity and optimizing the lipid metabolism when the dosage is halved.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a composition containing withaferin A and its application. Background technique [0002] With the continuous improvement of people's living standards, obesity and related diseases such as diabetes, hyperlipidemia, fatty liver, cardiovascular and cerebrovascular diseases, etc., which were previously common in western developed countries and related to energy metabolism, are now becoming more and more important. An important disease that threatens the health of the Chinese population. In addition, obesity is a risk factor for cancers, especially colon, rectal, prostate, breast, uterine and cervical cancers. According to statistics, the incidence rates of overweight and obesity among Chinese adults are 30.6% and 12.0% respectively. [0003] Metabolic syndrome is a group of clinical syndromes with central obesity, hyperglycemia, hyperlipidemia, and hypertension, which seriously af...

AI Technical Summary

Problems solved by technology

However, only a small percentage of people are able to maintain long-term weight loss by restricting diet and exercise. In addition, despite the obvious benefits of surgical treatment, the risks of surgery are still prohibitive for many people. Therefore, the difficulty of losing weight has led to increased attention to other treatment avenues , especially pharmacological interventions and treatments

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