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Disinfectant for killing mycobacterium tuberculosis effectively and preparation method and application of disinfectant

A technology of Mycobacterium tuberculosis, sterilization and disinfection, applied in the directions of medical preparations, disinfectants, bactericides containing active ingredients, etc., can solve the problems of toxicity and corrosiveness, persistent and difficult infection, DNA damage, etc., and achieve good safety Sex, improve the disinfection effect, the effect of non-irritating skin

Inactive Publication Date: 2019-05-17
HEILONGJIANG TIANXINGJIAN PHARMA TECH DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These disinfectants have a good killing effect on microorganisms but also have different side effects. For example, iodine-containing disinfectants can cause allergies, chlorine-containing disinfectants are corrosive, and aldehyde-containing disinfectants are strongly irritating and toxic. And corrosive, peroxide disinfectants can cause DNA damage, gene mutation, carcinogenic, etc.
[0003] Mycobacterium tuberculosis mainly invades people with low immunity or as a continuous infection and infection with other diseases, so opportunistic pathogenicity is its distinctive feature. Mycobacterium tuberculosis is mostly resistant to general anti-tuberculosis drugs and often causes persistent infection Refractory

Method used

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  • Disinfectant for killing mycobacterium tuberculosis effectively and preparation method and application of disinfectant
  • Disinfectant for killing mycobacterium tuberculosis effectively and preparation method and application of disinfectant
  • Disinfectant for killing mycobacterium tuberculosis effectively and preparation method and application of disinfectant

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Effect test

Embodiment 1

[0034] A disinfectant for efficiently killing Mycobacterium tuberculosis, comprising 30% to 80% by weight of levulinic acid, 3% to 10% by weight of sodium dodecylbenzenesulfonate, and 10% to 65% by weight of water. The pH value is set at 2~6.

[0035] Preferably, the weight percentage of levulinic acid is 40%~75%; the weight percentage of sodium dodecylbenzenesulfonate is 4%~8%; the weight percentage of water is 10%~56%, and the pH is preferably 2~5 , the optimum pH is 2.5. The disinfectant is in the form of aqueous solution.

Embodiment 2

[0037] A disinfectant for efficiently killing Mycobacterium tuberculosis comprises 50% by weight of levulinic acid, 5% by weight of sodium dodecylbenzenesulfonate, and 45% by weight of water.

[0038] Or a highly efficient disinfectant for killing Mycobacterium tuberculosis, comprising 30% by weight of levulinic acid, 5% by weight of sodium dodecylbenzenesulfonate, 65% by weight of water, and a pH of 2.5.

Embodiment 3

[0040] A disinfectant for efficiently killing Mycobacterium tuberculosis comprises 80% by weight of levulinic acid, 8% by weight of sodium dodecylbenzenesulfonate, and 12% by weight of water.

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Abstract

The invention discloses a disinfectant for killing mycobacterium tuberculosis effectively and a preparation method and application of the disinfectant. The disinfectant is mainly prepared from the following components of levulinic acid (LAV), sodium dodecyl benzene sulfonate (SDBS) and the like. According to the disinfectant for killing mycobacterium tuberculosis effectively and the preparation method and application of the disinfectant, LAV-SDBS can kill the mycobacterium tuberculosis and multi-drug resistant mycobacterium tuberculosis rapidly and effectively, is used for live or non-living disinfection, shows activity against a wide range of microorganisms, such as viruses, fungi, or bacteria, especially for the mycobacterium tuberculosis and the multi-drug resistant mycobacterium tuberculosis, the good sterilization and disinfection effects are achieved, airborne transmission of the mycobacterium tuberculosis can be cut off, the effective speed is high, the effective time is long, continuous bacteriostat can be achieved, the side effects are avoided, and good substitutability and security are achieved.

Description

[0001] Technical field: The present invention relates to the technical field of disinfection, in particular to a disinfectant for efficiently killing Mycobacterium tuberculosis and its preparation method and application. The present invention also relates to the application of said disinfectant for disinfection of live or non-living bodies, especially effective against Mycobacterium tuberculosis. Background technique: [0002] Disinfection is to kill pathogenic microorganisms on the transmission medium, make them harmless, eliminate pathogenic microorganisms outside the human body, cut off the transmission of infectious diseases, and achieve the purpose of controlling infectious diseases. Currently commonly used disinfectants are iodine-containing, chlorine-containing, aldehyde-containing and peroxides. These disinfectants have a good killing effect on microorganisms but also have different side effects. For example, iodine-containing disinfectants can cause allergies, chlorin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N37/42A01N41/04A01N37/44A01N43/16A01N43/04A61K31/717A61K31/19A61K31/185A61K31/197A61K31/336A01P3/00A01P1/00A61P31/02A61P31/04A61P31/10
CPCY02A50/30
Inventor 周利
Owner HEILONGJIANG TIANXINGJIAN PHARMA TECH DEV
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