Coronary flow reserve score calculating method based on ultrasonic and CT imaging technology

A technology of coronary blood flow and fractional reserve, applied in the fields of biomedical engineering and biomechanics, can solve problems such as the impact of pertinence and accuracy, without considering the individual situation of patients, and achieve the effect of improving accuracy

Inactive Publication Date: 2019-04-26
BEIJING UNIV OF TECH
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Problems solved by technology

But the current coronary FFR CT The boundary conditions such as blood flow in the calculation process do not consider the individualized situation of the patient, but are estimated from the patient's physiological parameters such as blood pressure, heart rate, and myocardial mass. CT The impact on the pertinence and accuracy of calculation is more significant

Method used

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  • Coronary flow reserve score calculating method based on ultrasonic and CT imaging technology
  • Coronary flow reserve score calculating method based on ultrasonic and CT imaging technology
  • Coronary flow reserve score calculating method based on ultrasonic and CT imaging technology

Examples

Experimental program
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Embodiment Construction

[0035] The following examples illustrate the specific implementation of the above process.

[0036] (1) Three-dimensional model reconstruction based on coronary CT images ( Figure 4 ). Three-dimensional reconstruction requires the use of software tools such as Mimics. Keep at least blood vessels with a diameter > 1 mm.

[0037] (2) According to the blood flow velocity data of the three main coronary vessels LAD / LCX / RCA measured by ultrasound, calculate the blood flow of the three main vessels according to the formula (2), such as: Q LAD , Q LCX and Q RCA .

[0038] (3) calculation Figure 4 The volume of branch vessels at all levels. The volume V of each branch vessel segment can be obtained by using software tools such as Mimics ij .

[0039] Follow the formula below to calculate the flow rate of each branch of the coronary artery layer by layer.

[0040]

[0041]

[0042] (4) Set the blood vessel wall as a rigid wall; blood is an incompressible Newtonian flu...

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Abstract

A coronary flow reserve score calculating method based on ultrasonic and CT imaging technology relates to the field of biomedical engineering and biomechanics. The method mainly settles a technical problem of obtaining a coronary blood flow according to coronary ultrasonic technology and distributing the blood flow volume of each branch of the coronary vein, thereby supplying an accurate-number individualized boundary condition for noninvasive FFRCT calculation, and ensuring high accuracy in FFRCT number simulated calculation. The method of the invention can obtain the individualized blood flow volume information of each branched blood vessel of a patient coronary vein through the coronary ultrasonic blood flow data of the patient, and supplies an accurate boundary condition for FFRCT calculation, thereby improving FFRCT calculation accuracy.

Description

technical field [0001] The invention relates to the fields of biomedical engineering and biomechanics, and uses medical image processing technology, hemodynamic numerical simulation technology, coronary Doppler echocardiography and CT imaging technology in clinical medicine. Background technique [0002] Fractional coronary flow reserve (FFR) is currently a "gold standard" clinically used to diagnose coronary stenosis, but its clinical application is limited due to its invasiveness. Fractional coronary flow reserve (FFR) based on CT images and computational fluid dynamics CT ) calculation method has received great attention from researchers because of its non-invasive measurement. But the current coronary FFR CT The boundary conditions such as blood flow in the calculation process do not consider the individualized situation of the patient, but are estimated from the patient's physiological parameters such as blood pressure, heart rate, and myocardial mass, which have a gr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G16H50/50
CPCG16H50/50
Inventor 乔爱科夏骏张宏辉柳思聪杨印龙
Owner BEIJING UNIV OF TECH
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