Method for preparing gold-doped fluorescent carbon quantum dots

Abstract

The invention provides a method for preparing gold-doped fluorescent carbon quantum dots. The method comprises the following steps: preparing an aqueous solution of a gold nanocluster-supported modified chitosan compound; and uniformly mixing the aqueous solution of the gold nanocluster-supported modified chitosan compound with an aqueous citric acid solution, and carrying out a hydrothermal reaction to obtain the gold-doped fluorescent carbon quantum dots. The double-fluorescence emission wavelength gold-doped fluorescent carbon quantum dots with the advantages of low toxicity, good biocompatibility, good water solubility, high fluorescence yield and good storage stability can be provided through the method.

Description

technical field [0001] The invention belongs to the field of medical biochemical detection, and in particular relates to a gold-doped fluorescent carbon quantum dot with dual fluorescence emission wavelengths and a preparation method thereof. Background technique [0002] In recent years, the most widely used quantum dot materials have attracted the attention of researchers. However, in recent years, studies have shown that quantum dots contain heavy metals such as chromium and selenium, which are highly toxic. Therefore, many scientists are working hard to find new alternatives. Carbon quantum dot (CQD, carbon quantum dot) is a newly developed carbon nanomaterial, which is made of sp 2 Fluorescent nanoparticles composed of hybrid carbon or amorphous carbon, which can emit light stably, have a size of less than 10 nm, and have a quasi-spherical structure are expected to replace semiconductor quantum dots as medical fluorescent materials. In recent years, many carbon sources...

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Problems solved by technology

[0006] At present, most of the reported carbon quantum dots have low fluorescence quantum yields, which limits their practical applications in various fields. Some carbon quantum dots lack effective recognition groups on the surface, resulting in limited specific binding ability to targets. Poor selectivity; most biochemical sensors based on carbon quantum dots use the change of a single fluorescence emission intensity as the signal output unit, and there is a problem that the fluorescence intensity is easily interfered by factors such as the intensity of the excitation light source and the concentration of the probe, resulting in a lack of detection accuracy. improve

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