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Chestnut Bark Extract

A technology of extract and chestnut skin, which is applied in the field of chestnut skin extract, can solve the problems that cannot be easily and difficult to achieve self-digestion state, and there is no production of free ceramide

Active Publication Date: 2022-07-01
SATICINE MEDICAL CO LTD
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Therefore, since glycosphingolipids and sphingomyelin are produced and utilized in large quantities in nature, free ceramide cannot be easily obtained in large quantities from raw materials existing in nature, and it is even more difficult to obtain a large amount of free ceramide, which is the basic skeleton Free ceramide with the chemical structure of human body
[0010] In particular, for the production of free ceramides from plants, it is difficult to achieve the necessary self-digestion state for converting acidic sphingolipids into free ceramides, both in nature and industrially, and thus, there has been no Technology for efficient production of free ceramides from plants
For example, Patent Document 1 describes a method for producing a ceramide concentrate, which includes extracting the alcohol extract of the distillation residue obtained by distilling the fermented glutinous rice of purple sweet potato with acetone or hexane and recovering the residue, and also describes the concentrated The product contains free ceramide, but in this production method, it is necessary to go through the step of distilling the fermented grains of purple sweet potato to obtain the distillation residue

Method used

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Embodiment

[0136] The present invention will be specifically described below, but the present invention is not limited to the following examples. In addition, in the following examples, unless otherwise specified, ceramide AP means ceramide AP1, and ceramide DP means ceramide AP2. In addition, the % symbol of ethanol represents the ethanol volume % in the ethanol aqueous solution. For example, 95% ethanol means 95 v / v% ethanol in ethanol in water.

[0137] Preparation of chestnut skin

[0138] The variety "ぽろたん" in which the chestnut skin is easily peeled off from the seed part (edible part) was used in the study. The weight ratio of chestnut skins to seeds is about 30:70. The average moisture ratio of the inner skin and outer shell after manual peeling was about 30%, respectively. The average weight ratio of the inner skin and the outer skin of the dried chestnut skin was 68:32.

[0139] Analysis of the shell and endothelium

[0140] The outer shell and the inner skin were pul...

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Abstract

Provided are a method for efficiently producing free ceramide (especially human-type free ceramide) and the like. The extract obtained from chestnut bark contains relatively abundant free ceramides and glucosylceramides, which is useful. In addition, chestnut bark acetone extract has ultraviolet absorption and ultraviolet wavelength conversion actions, which is useful.

Description

technical field [0001] The present invention relates to chestnut bark extract. Moreover, this invention also relates to the manufacturing method (extraction method) and use of this extract. Background technique [0002] Regarding sphingolipids, the basic skeleton is a ceramide in which a long-chain fatty acid is bound to the amino group of a sphingosine base, which is a long-chain amino alcohol, and a polar group such as a sugar and phosphoric acid is bound to an alcohol hydroxyl group. state exists in the cell membrane. Among them, glycosylceramide, which is a glycosphingolipid, is a component widely present in animals, plants, and microorganisms, and is also called cerebroside. In recent years, it is also a functional substance that has been attracting attention due to its role in regulating biological functions. . [0003] Among glycosylceramides, glucosylceramides (glycosphingolipids in which glucose is bound to ceramides), which are widely present in plants and fungi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9789A23L33/105A61K36/49A61P17/00A61Q19/00A61K31/164
CPCA61Q19/00A61K31/164A61K36/49A23L33/105A61K8/9789A61P17/00
Inventor 柚木惠太
Owner SATICINE MEDICAL CO LTD
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