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Application of cycloastragenol to preparation of medicines for preventing or treating acne

A technology of cycloastragalus and medicine, applied in the field of medicine, can solve the problems such as cycloastragalus that have not been found yet, and achieve the effects of no drug dependence, remarkable curative effect and low cost

Inactive Publication Date: 2019-03-29
JIANGSU YONGJIAN PHARMA TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] At present, there is no report that cycloastragenol has been used to prepare drugs for the prevention or treatment of acne

Method used

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  • Application of cycloastragenol to preparation of medicines for preventing or treating acne

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] The preparation of embodiment 1 capsule

[0025] Take 50 g of cycloastragenol and 60 g of microcrystalline cellulose and pass through a 80-mesh sieve, mix evenly, pass through a 40-mesh sieve to granulate, dry at 60°C for 30 min, granulate, add 20 g of magnesium stearate, mix evenly, granulate, ring The content of astragalol is 20 mg / tablet.

Embodiment 2

[0026] The preparation of embodiment 2 tablet

[0027] Pass 30g of cycloastragenol, 80g of lactose, and 30g of starch through a 80-mesh sieve, mix well, add appropriate amount of starch slurry to make a soft material, pass through a 20-mesh sieve to granulate, dry in an oven at 60°C, pass through a 14-mesh sieve for granulation, Add 6 g of carboxymethyl starch sodium and 4 g of magnesium stearate, mix well and then press into tablets to make a tablet with a tablet weight of 200 mg / tablet and a content of cycloastragenol of 40 mg / tablet.

Embodiment 3

[0028] The preparation of embodiment 3 gel

[0029] Take 0.3% Cycloastragenol, 4% Butylene Glycol, 1% PEG / PPG-14 / 7 Dimethyl Ether, 0.5% Panthenol, 0.01% Sodium Hyaluronate, 0.4% Acrylates / C10-30 Alkyl acrylate crosspolymer, 0.15% carbomer, 0.06% disodium EDTA, 0.18% potassium hydroxide, 0.5% 1,2-hexanediol, caprylyl glycol, the rest purified water, according to the gel The conventional preparation method is worth cycloastragenol gel.

[0030] Method of use: Oral administration, 2 times a day, 100-200mg each time, 1 week is a course of treatment. For external use, 1-2 times a day, 1 week is a course of treatment, apply evenly on the face until it is fully absorbed, and the effect is better when used before going to bed. If it is not used externally, it can be cured only by oral administration, but the treatment time can be shortened by adding external application.

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Abstract

The invention provides request for protection of an application of cycloastragenol to preparation of medicines for preventing or treating acne for the first time because the cycloastragenol has obvious effects of removing ache and eliminating skin ulcers in vivo and in vitro, and belongs to the field of new purposes of the cycloastragenol. The cycloastragenol has the effects of resisting ageing, nourishing the liver, protecting the livers, preventing and treating cardiac failure and the like according to known information. The situation that the cycloastragenol is applied to preparation of themedicines for preventing or treating acne is provided, medicines in various preparation formulations, which are taken orally and externally used can be prepared, and the new purpose of the cycloastragenol is developed. A medicine which is safe, effective, precise in treatment effects and small in toxic and side effects is provided for prevention or treatment of the acne, and therefore the cycloastragenol has great medical application prospects.

Description

technical field [0001] The invention belongs to the technical field of medicine, and relates to a new application of a known medicine, in particular to the application of a cycloastragenol in the preparation of a medicine for preventing or treating acne, and more specifically to the preparation of a triterpenoid saponin compound cycloastragenol Use in medicines for preventing or treating acne and application of pharmaceutical composition containing cycloastragenol. Background technique [0002] Acne, also known as acne, pimples, acne, pimples or folliculitis, is a chronic inflammatory skin disease involving the pilosebaceous glands. It is one of the most common diseases in cosmetic dermatology. This kind of skin disease is more common in adolescence, but it is not completely related to age. At present, more and more adults are also troubled by acne. Traditional Chinese medicine believes that the yang heat of the body is relatively strong, coupled with the vigorous vitality ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/58A61P17/10
CPCA61K31/58A61P17/10
Inventor 顾正兵梁延春刘艳芳陶月红侯中海曾铖
Owner JIANGSU YONGJIAN PHARMA TECH CO LTD
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