Detection method of main active ingredients in folium ginkgo-radix salviae miltiorrhizae vasodistal soft capsule

Abstract

The invention discloses a detection method of main active ingredients in a folium ginkgo-radix salviae miltiorrhizae vasodistal soft capsule. 1000 folium ginkgo-radix salviae miltiorrhizae vasodistalsoft capsules are prepared from 500 g of folium ginkgo, 500 g of radix salviae miltiorrhizae, 300 g of herba erigerontis, 300 g of fiveleaf gynostemma herb, 400 g of fructus crataegi, 400 g of garlic,200 g of radix notoginseng and 10 g of blumea camphor. The detection method comprises the steps of quantitatively analyzing flavonoid constituents, phenolic acids and the like, wherein the quantitative analysis method is a high-performance liquid-phase chromatography-mass spectrometry. The detection method has the advantages of higher main ingredient quantitative analysis sensitivity to the folium ginkgo-radix salviae miltiorrhizae vasodistal soft capsule, good precision, high identification capacity, capability of detecting more ingredients, and good detection data accuracy; and the batch similarity of the qualitative analysis of the folium ginkgo-radix salviae miltiorrhizae vasodistal soft capsule is good, and the overall chemical contour of the folium ginkgo-radix salviae miltiorrhizaevasodistal soft capsule can be better reflected.

Description

technical field [0001] The invention relates to the technical field of detection methods for Yindan Xinnaotong soft capsules, in particular to a detection method for main effect components in Yindan Xinnaotong soft capsules. Background technique [0002] Yindan Xinnaotong Soft Capsule is made of 8 traditional Chinese medicines including Ginkgo biloba, Salvia miltiorrhiza, Gynostemma pentaphyllum, Erigeron breviscapus, garlic, Panax notoginseng, hawthorn, and natural borneol. The existing detection method of main effect components in Yindan Xinnaotong soft capsules includes quantitative analysis of main effect components in Yindan Xinnaotong soft capsules and qualitative analysis of Yindan Xinnaotong soft capsules. The quantitative analysis of the main effect components in Yindan Xinnaotong soft capsules is generally detected by chromatography, which has insufficient sensitivity, poor accuracy, poor identification ability, few detectable components, and poor detection data ac...

AI Technical Summary

Problems solved by technology

The quantitative analysis of the main effect components in Yindan Xinnaotong soft capsules is generally detected by chromatography, which is not sensitive enough, has poor accuracy, poor identification ability, few detectable components, and poor detection data accuracy

The similarity between batches of qualitative analysis of Yindan Xinnaotong Soft Capsules is poor, which cannot well reflect the overall chemical profile of Yindan Xinnaotong Soft Capsules

[0003] Therefore, the existing detection method of the main effect components in Yindan Xinnaotong soft capsules, the sensitivity of the quantitative analysis of the main effect components in Yindan Xinnaotong soft capsules is not high enough, the accuracy is poor, and the discrimination ability is poor, and the detectable There are few ingredients, and the accuracy of detection data is poor; the similarity between batches of qualitative analysis of Yindan Xinnaotong Soft Capsules is poor, which cannot well reflect the overall chemical profile of Yindan Xinnaotong Soft Capsules

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