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Synbiotic compound preparation facilitating improvement of type-2 diabetes and complications of diabetes and preparation method of synbiotic compound preparation

A technology for type 2 diabetes and compound preparations, which can be applied to medical preparations containing active ingredients, bacteria used in food preparation, metabolic diseases, etc. Biochemical indicators such as blood lipids and oxidative stress are improved, synergistic effect is improved, and the effect of increasing the applicable population

Inactive Publication Date: 2019-03-19
江苏宏众百德生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The ability to produce insulin in patients with type 2 diabetes is not completely lost, but due to various reasons, the efficiency of insulin in promoting glucose uptake and utilization decreases, insulin resistance occurs, and the body compensatoryly secretes excessive insulin to produce hyperinsulinemia
[0004] However, the single use of probiotics and prebiotics has different mechanisms for their respective functions, and even the same probiotics / prebiotics will show great differences in people with different genetic backgrounds and living habits
At present, the active ingredients of existing products are mostly single strains or single prebiotics, which makes the synbiotics compound preparation unable to adapt to a wide range of people; therefore, the present invention proposes a synbiotics that can help improve type 2 diabetes and its complications. Elemental compound preparation and preparation method thereof

Method used

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  • Synbiotic compound preparation facilitating improvement of type-2 diabetes and complications of diabetes and preparation method of synbiotic compound preparation

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Embodiment 1

[0020] The invention provides a technical solution: a synbiotic compound preparation that helps to improve type 2 diabetes and its complications. The formula of the improved synbiotic compound preparation includes the following components: Bifidobacterium animalis subspecies lactis 5% , Bifidobacterium bifidum 6%, Lactobacillus acidophilus 8%, Lactobacillus reuteri 2%, Lactobacillus gasseri 3%, inulin 2%, fructooligosaccharides 4%, xylooligosaccharides 8%, b Dextran 5%, glucomannan 8%, hydroxypropyl methylcellulose 2%, psyllium husk powder 3%.

[0021] Among them, Bifidobacterium animalis subsp. lactis, Bifidobacterium bifidum, Lactobacillus acidophilus, Lactobacillus reuteri and Lactobacillus gasseri are all in the list of strains that can be used in food issued by the Ministry of Health of my country.

[0022] A kind of preparation method of the above-mentioned synbiotics compound preparation that helps to improve type 2 diabetes and its complications, the preparation method...

Embodiment 2

[0028] The invention provides a technical solution: a synbiotic compound preparation that helps to improve type 2 diabetes and its complications. The formula of the improved synbiotic compound preparation includes the following components: Bifidobacterium animalis milk subspecies 6% , Bifidobacterium bifidum 7%, Lactobacillus acidophilus 9%, Lactobacillus reuteri 3%, Lactobacillus gasseri 4%, inulin 3%, fructooligosaccharides 5%, xylooligosaccharides 9%, b Glucan 6%, glucomannan 9%, hydroxypropyl methylcellulose 3%, psyllium husk powder 3%.

[0029] Among them, Bifidobacterium animalis subsp. lactis, Bifidobacterium bifidum, Lactobacillus acidophilus, Lactobacillus reuteri and Lactobacillus gasseri are all in the list of strains that can be used in food issued by the Ministry of Health of my country.

[0030] A kind of preparation method of the above-mentioned synbiotics compound preparation that helps to improve type 2 diabetes and its complications, the preparation method co...

Embodiment 3

[0036] The invention provides a technical solution: a synbiotic compound preparation that helps to improve type 2 diabetes and its complications. The formula of the improved synbiotic compound preparation includes the following components: Bifidobacterium animalis milk subsp. 7% , Bifidobacterium bifidum 8%, Lactobacillus acidophilus 10%, Lactobacillus reuteri 4%, Lactobacillus gasseri 5%, inulin 4%, fructooligosaccharides 6%, xylooligosaccharides 10%, b Dextran 7%, Glucomannan 10%, Hydroxypropyl Methyl Cellulose 4%, Psyllium Husk Powder 5%.

[0037] Among them, Bifidobacterium animalis subsp. lactis, Bifidobacterium bifidum, Lactobacillus acidophilus, Lactobacillus reuteri and Lactobacillus gasseri are all in the list of strains that can be used in food issued by the Ministry of Health of my country.

[0038] A kind of preparation method of the above-mentioned synbiotics compound preparation that helps to improve type 2 diabetes and its complications, the preparation method c...

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Abstract

The invention discloses a synbiotic compound preparation facilitating improvement of type-2 diabetes and complications of the diabetes. The synbiotic compound preparation comprises, in weight percent,5%-10% of animal bifidobacterium lactobacillus subspecies, 6%-9% of bifidobacterium bifidum, 8%-12% of lactobacillus acidophilus, 2% -6% of lactobacillus reuteri, 3%-8% of lactobacillus gasseri, 2%-6% of Inulin, 4%-8% of ructo oligosaccharide, 8%-11% of xylo-oligosaccharide, 5%-9% of beta-glucan, 8%-11% of glucomannan, 2%-4% of hydroxypropyl methyl cellulose and 3%-6% of psylliumseedhusk powder.The invention further discloses a preparation method of the synbiotic compound preparation facilitating improvement of the II-type diabetes and complications of the diabetes. The preparation method includes the steps: probiotic culture; probiotic fermentation; freeze drying; uniformly blending and sub-packaging. The compound preparation has improving effects on insulin resistance, biochemical criterions of blood glucose and blood fat and oxidative stress, obvious auxiliary treatment effects on current treatment schemes and no obvious side effects.

Description

technical field [0001] The invention relates to the technical field of preparation of synbiotic compound preparations, in particular to a synbiotic compound preparation and a preparation method thereof which are helpful for improving type 2 diabetes and its complications. Background technique [0002] Diabetes is a metabolic disease characterized by hyperglycemia. Hyperglycemia is caused by defective insulin secretion or impaired biological action, or both. Long-term high blood sugar in diabetic patients will lead to chronic damage and dysfunction of various tissues, especially the eyes, kidneys, heart, blood vessels, and nervous system. Among them, type 2 diabetes, also known as adult-onset diabetes, mostly occurs after the age of 35-40, accounting for more than 90% of diabetic patients. The ability to produce insulin in patients with type 2 diabetes is not completely lost, but due to various reasons, the efficiency of insulin to promote glucose uptake and utilization dec...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/68A23L2/39A23L33/00A61P3/10A61P5/50A61P3/06A61K35/745A61K35/747A61K31/733A61K31/702A61K31/716A61K31/736A61K31/717
CPCA61P3/06A61P3/10A61P5/50A23L2/39A23L33/00A61K31/702A61K31/716A61K31/717A61K31/733A61K31/736A61K35/745A61K35/747A61K36/68A23V2002/00A23V2400/145A23V2400/173A23V2400/113A23V2400/517A61K2300/00A23V2200/3262A23V2200/328A23V2200/30A23V2250/28A23V2250/5034A23V2250/5062A23V2250/5058A23V2250/51088A23V2250/5116
Inventor 张军毅李东尧单锴周克茹
Owner 江苏宏众百德生物科技有限公司
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