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A method and system for optimizing cardiac valve replacement

A technology for heart valve replacement and optimization methods, applied in image data processing, 3D modeling, instruments, etc., can solve problems such as weakening the efficacy of TAVR, early degeneration and dysfunction of TAVR prostheses, and achieve the effect of reducing clinical risks.

Active Publication Date: 2019-02-19
TONGJI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Improper implantation (valve size selection) will lead to early degeneration and dysfunction of the TAVR prosthesis
In addition, the severity and distribution of valve leaflet calcification can impair the efficacy of TAVR

Method used

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  • A method and system for optimizing cardiac valve replacement
  • A method and system for optimizing cardiac valve replacement
  • A method and system for optimizing cardiac valve replacement

Examples

Experimental program
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Effect test

Embodiment

[0033] When the TAVR prosthesis is deployed on the wall of the aortic root, the region of the aortic annulus, the stress from the expansion of the periprosthetic stent will cause a local displacement / motion response of the annulus. Therefore, the change in the annulus is directly proportional to the stress. Second, the annular stress will dynamically change the morphology of the aortic root before the aortic prosthetic valve is placed. For the most effective results, the aortic valve device should be deployed near a uniform distribution of calcification, where the valve leaflets are still malleable, and where the calcified areas do not block the function of the periprosthetic valve leaflets. If the aortic valve leaflets are heavily calcified and unevenly distributed, excessive stress on the stent can obstruct the function of the periprosthetic valve and lead to early failure of TAVR. Therefore, the postoperative biomechanical characteristics (stress) of the aortic tissue are ...

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Abstract

The invention relates to a method and a system for optimizing cardiac valve replacement. The method comprises the following steps: (1) calculating load forces of different patients after transcatheteraortic valve replacement; (2) simulating the behavior of aortic root and valve tissue, and extracting biomechanical characteristics by finite element method; (3) establishing an aortic valve insufficiency risk prediction model; (4) using the risk prediction model to predict the risk of heart valve and optimize the prosthetic valve, repeating the steps (1)-(3) until the risk prediction results aresafe. As compare with that prior art, the method and system of the present invention can guide doctors to use different optimize valves for different patients to minimize clinical risks.

Description

technical field [0001] The invention relates to a heart valve optimization method and system, in particular to a heart valve replacement optimization method and system. Background technique [0002] Aortic stenosis (AS) is a degenerative valve disease in the elderly that worsens over time. The pathophysiology of aortic stenosis is degenerative and calcific, and is likely exacerbated by the same cellular atherosclerotic processes involved in lipid accumulation and inflammation. Symptomatic patients with calcified aortic stenosis can be treated with a minimally invasive procedure called transcatheter aortic valve replacement (TAVR). TAVR consists of the percutaneous implantation of a biological heart valve mounted within a metal stent. TAVR has revolutionized the management of symptomatic severe aortic stenosis in patients at high or intermittent risk for surgical aortic valve replacement (SAVR), such as shock, age >80 years, renal insufficiency, diabetes, etc. TAVR was ...

Claims

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Application Information

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IPC IPC(8): G06T17/20
CPCG06T17/205G06T2207/30048G06T2207/10081Y02T90/00
Inventor 周小波
Owner TONGJI UNIV
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