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Anastomotic nail and preparation method and application thereof

A staple and magnesium alloy technology, applied in the field of staple and its preparation, can solve the problems of non-degradability, toxicity, poor biocompatibility, etc., and achieve the effects of alleviating stress shielding effect, high yield strength, and good biological safety

Inactive Publication Date: 2019-01-29
北京普润医疗器械有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0006] The purpose of the present invention is to provide a staple and its preparation in order to overcome the defects of non-degradable, toxic, poor biocompatibility and need for secondary surgery to overcome the existing titanium alloy or pure titanium metal material of the staple. Method and application, the staple provided by the present invention has the advantages of degradability, non-toxicity, good biocompatibility, and no need for secondary surgery to take it out.

Method used

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  • Anastomotic nail and preparation method and application thereof

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Embodiment 1-7 and comparative example 1-7

[0050] In weight percentage, each component in the composition of the magnesium alloy is mixed to prepare the magnesium alloy raw material. Put the prepared alloy raw material in a melting furnace for melting, feed 99.99% high-purity argon gas into the melting process, and smelt at a temperature of 720° C. for 30 minutes. The obtained melt is poured into a metal mold, and after cooling, a magnesium alloy ingot is obtained. Subsequently, the magnesium alloy ingot was subjected to homogenization treatment at 350° C. for 12 hours, and the homogenized alloy ingot was directly subjected to hot extrusion with an extrusion ratio of 17 and an extrusion temperature of 250° C. to obtain Primary billet. The primary billet is cut and turned, and then quenched after solution treatment at 300°C for 8 hours to form a secondary billet. Afterwards, the obtained secondary blank is subjected to multi-pass continuous drawing to form a magnesium alloy wire with a diameter of 0.23 mm. Wherein, i...

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Abstract

The invention relates to the field of medical metal materials, and discloses an anastomotic nail and a preparation method and an application thereof. A material of the anastomotic nail is a magnesiumalloy, and with the total amount of the magnesium alloy as a benchmark, the magnesium alloy contains, by weight, the following elements: 0.01-3% of Al, 0.01-1% of Sn and 95-99% of Mg. The anastomoticnail has the characteristics of both high yield strength and appropriate degradation rate, appropriate specific strength and specific stiffness, and good bio-safety, can ensure that a sutured human tissue or organ is free from infection and has no any damage, and is expected to achieve large-scale practical clinical applications.

Description

technical field [0001] The invention relates to the field of medical metal materials, in particular to a staple and its preparation method and application. Background technique [0002] The staples currently used in clinical staplers are mainly pure titanium or titanium alloys, which have good corrosion resistance and can maintain structural stability for a long time in the body, but there are also some disadvantages, such as titanium alloys in the body due to Friction in the body produces wear debris and toxic ions due to corrosion, causing local allergic reactions or inflammation and reducing biocompatibility. In addition, titanium alloy is a non-degradable material. For short-term implantation, after the recovery of human tissue function, it needs to be removed through a second operation, which increases the pain of patients and the burden of medical expenses. [0003] Therefore, magnesium alloys and their composites have become a new generation of high-strength, low-mod...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C22C23/02C22C23/00C22C1/02A61B17/115
CPCC22C23/02A61B17/1114A61B17/115A61B2017/00526C22C1/02C22C23/00
Inventor 张静王树果
Owner 北京普润医疗器械有限公司
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