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Preparation method of sundew film coating agent

A technology of sundew and film coating agent, which is applied in the directions of non-active ingredients medical preparations, medical preparations containing active ingredients, pharmaceutical formulas, etc. Treatment effect and other issues, to achieve the effect of small dosage, large fluidity and strong fluidity

Inactive Publication Date: 2018-12-11
PIZHOU GAXING MEDICINE TECH SERVICE CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The applicant utilizes this method to treat 10 cases of eczema and 6 cases of neurodermatitis. The residence time of the liquid medicine is short, which has a great influence on the therapeutic effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Weigh 200g of sundew extract, add 30g of borneol, 20g of menthol and stir until dissolved, then add 20g of dibutyl phthalate and 12.5g of polyvinyl formal, stir and mix evenly for later use; another 100g of acetone Add an equal amount of 75% v / v ethanol to mix, add to the well-mixed stock solution, then add 75% v / v ethanol to make the full amount to 1000g, mix well, divide into 25ml glass bottles, and screw the cap , sealed and ready to use; the 200g sundew extract is prepared by the following method: take sundew powder 100g, put it into a percolator, and use 5 times the concentration of 92% v / v ethanol to impregnate for 48h After that, press 0.8ml·min -1 Percolate at a speed of 100g, collect 100g of percolate and place it for later use; continue to collect 100g of percolate, press the slag, combine and concentrate the continued collection of percolate and squeezed liquid to 100g, take the spare percolate and concentrate The liquids were combined to obtain 200 g of sun...

Embodiment 2

[0016] Weigh 200g of sundew extract, add 30g of borneol, 20g of menthol and stir until dissolved, then add 20g of dibutyl phthalate and 12.5g of polyvinyl formal, stir and mix evenly for later use; another 100g of acetone Add an equal amount of 75% v / v ethanol to mix, add to the well-mixed stock solution, then add 75% v / v ethanol to make the full amount to 1000g, mix well, divide into 25ml glass bottles, and screw the cap , sealed to get final product; the 200g sundew extract is prepared by the following method: take sundew powder 100g, put it into a percolator, and use 5 times the concentration of 93% v / v ethanol to impregnate for 48h After that, press 0.8ml·min -1 Percolate at a speed of 100g, collect 100g of percolate and place it for later use; continue to collect 100g of percolate, press the slag, combine and concentrate the continued collection of percolate and squeezed liquid to 100g, take the spare percolate and concentrate The liquids were combined to obtain 200 g of...

Embodiment 3

[0018] Weigh 200g of sundew extract, add 30g of borneol, 20g of menthol and stir until dissolved, then add 20g of dibutyl phthalate and 12.5g of polyvinyl formal, stir and mix evenly for later use; another 100g of acetone Add an equal amount of 75% v / v ethanol to mix, add to the well-mixed stock solution, then add 75% v / v ethanol to make the full amount to 1000g, mix well, divide into 25ml glass bottles, and screw the cap , sealed to get final product; the 200g sundew extract is prepared by the following method: take sundew powder 100g, put it into a percolator, and use 5 times the concentration of 95% v / v ethanol to immerse for 48h After that, press 0.8ml·min -1 Percolate at a speed of 100 g, collect 100 g of percolate and put it aside for later use; continue to collect 100 g of percolate, squeeze the slag, combine and concentrate the continued collection of percolate and squeezed liquid to 100 g, take the spare percolate and concentrate The liquids were combined to obtain 2...

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PUM

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Abstract

The invention concretely discloses a preparation method of a sundew film coating agent. The sundew film coating agent is prepared from 200g of sundew extracts, 30g of borneol, 20g of menthol, 30g of dibutyl phthalate, 12.5g of poly(vinyl formalacetal), 100g of acetone and the balance ethanol being 75 v / v percent after the constant volume reaching to 1000g. The prepared external use film coating agent is coated onto the affected part when being used; after solvents are volatilized, a film is formed so as to protect the focus surface; meanwhile, the contained medicine is released to achieve thetreatment effect. The preparation process is very simple; mounting materials are not used; the use is convenient; the film coating agent is coated onto the affected part; after the film coating agentis dried after the coating, the film formed in the affected part has certain anti-tearing performance; the contained medicine can be absorbed in a balanced way to generate the curative effect.

Description

technical field [0001] The invention belongs to the field of medicine preparation for external use, and in particular relates to a preparation method of sundew varnish. Background technique [0002] Eczema and neurodermatitis are relatively frequent skin diseases, which bring pain to patients due to local itching of the epidermis. Because the focus of neurodermatitis is the epidermis, it often brings difficulties to the treatment, and it is difficult to achieve the curative effect of systemic treatment. Some courses of disease reach several years, seriously affecting the physical and mental health of patients. At present, skin lesions such as neurodermatitis and eczema are mostly treated locally with external preparations. Commonly used preparations include tincture, water, ointment, paste, lotion and other external preparations. There is a big gap in the treatment effect. Some patients have been treated repeatedly in a variety of ways, which not only delays the course of t...

Claims

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Application Information

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IPC IPC(8): A61K36/185A61K9/70A61P17/00A61P25/00A61K31/045
CPCA61K36/185A61K9/7015A61K31/045A61K47/32A61K2236/333A61P17/00A61P25/00A61K2300/00
Inventor 张奎昌汤先伟花丽张路
Owner PIZHOU GAXING MEDICINE TECH SERVICE CO LTD
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