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Preparation method of hydrogel medicine for treating chronic rhinitis

A technology of chronic rhinitis and hydrogel, which is applied in the direction of drug combination, drug delivery, and pharmaceutical formulation, can solve the problem of high recurrence rate of rhinitis, and achieve the effect of reasonable raw material formula, no toxic side effects, and good application environment

Inactive Publication Date: 2018-11-30
山东景仲生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although it has a certain therapeutic effect, it cannot fundamentally solve the problem, which causes a very high recurrence rate of rhinitis and brings great mental pressure to the patient.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] This embodiment relates to a preparation process of hydrogel medicine for treating chronic rhinitis, and its specific steps include:

[0014] (1) Wash and remove 5-8 parts of fresh cornus, 6-8 parts of Nepeta, 3-4 parts of Scrophulariaceae, 6-8 parts of black mustard ears, and remove dust; take 8-10 parts of fresh yam, 6 Wash ~8 parts, remove dust and cut into 3~5 cm segments; take 3~5 parts of fresh ginger slices, wash, remove dust and cut into slices with a thickness of 1~2 cm, add the above cleaned materials into ceramic jars Keep it for later use; take 6~8 parts of distilled water, 1~2 parts of starch and 1~2 parts of sodium chloride into the above-mentioned ceramic tank, stir evenly as the fermentation base material; Stir and ferment at 40°C for 2 to 4 days, collect the stirred mixture, mix the stirred mixture with the ethanol solution at a mass ratio of 1:3, filter, and collect the filtrate; put the filtrate into a ceramic tank, seal the container, and store it at...

Embodiment 2

[0020] This embodiment relates to another preparation process of hydrogel medicine for treating chronic rhinitis, and its specific steps include:

[0021] (1) Wash and remove 5-8 parts of fresh cornus, 6-8 parts of Nepeta, 3-4 parts of Scrophulariaceae, 6-8 parts of black mustard ears, and remove dust; take 6-8 parts of fresh yam, 6 parts of scallion Wash ~8 parts, remove dust and cut into 3~5 cm segments; take 3~5 parts of fresh ginger slices, wash, remove dust and cut into slices with a thickness of 1~2 cm, add the above cleaned materials into ceramic jars Keep it for later use; take 3~4 parts of distilled water, 1~2 parts of starch and 1~2 parts of sodium chloride into the above ceramic pot, stir evenly as the fermentation base; put the fermentation base into the fermentation tank, Stir and ferment at 30°C for 2 to 4 days, collect the stirred mixture, mix the stirred mixture with ethanol solution at a mass ratio of 1:3, filter, and collect the filtrate; put the filtrate int...

Embodiment 3

[0027] This example relates to the use and method of a hydrogel drug for treating chronic rhinitis: first clean the nasal mucus in the nasal cavity, use a clean cotton swab dipped in salt water to wipe the nasal cavity; then soak the towel with hot water and cover the nose 3 to 4 minutes, then use a clean cotton swab to dip in an appropriate amount of the hydrogel for treating chronic rhinitis prepared by the present invention, and apply it repeatedly to the inside of the nasal cavity for 2 to 3 times; use it 3 to 4 times a day, with an appropriate amount each time, for For the treatment of chronic rhinitis, the effect of half a month of medication is obvious, and the effective rate of treatment is over 93%.

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PUM

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Abstract

The invention belongs to the field of medicine preparation technologies and relates to a preparation method of a hydrogel medicine for treating chronic rhinitis. Natural plant ingredients are used asmain raw materials and the ingredients permeate in hydrogel to form the medicine for preventing and treating nasal diseases. The raw materials comprise cornus canadensis, catnip, radix scrophulariae,charred schizonepeta spike, Chinese yam, fistular onion bulb, ginger slice, distilled water, starch, sodium chloride, coptis, licorice, balloonflower root, xanthium, Centipeda minima, flos magnoliae liliflorae, senecio, old luffa stem, ethanol and hydrogel. The preparation method comprises the following steps: preparation of a first concentrate of the natural plants, preparation of a second concentrate of the natural plants, preparation of luffa stem powder and preparation of the product. As the medicine is in the form of hydrogel, it can be ensured that the medicine can fully reach the nasalcavity, and the uncomfortable symptom caused by a spray which enters the throat also can be overcome. The hydrogel medicine has good efficacy. In addition, the prepration process is simple, the raw material formula is reasonable, the hydrogel medicine has no toxic or side effect, and the application environment is good.

Description

Technical field: [0001] The invention belongs to the technical field of medicine preparation, and relates to a preparation method of a hydrogel medicine for treating chronic rhinitis. The natural plant component is used as a main raw material, and the component is infiltrated into the hydrogel to form a medicine for preventing and treating nasal diseases. Background technique: [0002] Rhinitis is an inflammatory disease of the nasal cavity, which is the inflammation of the nasal mucosa caused by viruses, bacteria, allergens, various physical and chemical factors, and certain systemic diseases. The main pathological changes of rhinitis are congestion, swelling, exudation, hyperplasia, atrophy or necrosis of nasal mucosa. Typical symptoms of rhinitis usually manifest as nasal congestion, runny nose, sneezing, rhinitis-type headache, dizziness, etc. Rhinitis not only affects the nose, long-term intermittent or alternating nasal congestion can lead to dizziness and brain swell...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61K9/06A61P11/02
CPCA61K9/0043A61K9/06A61K36/28A61K36/346A61K36/40A61K36/42A61K36/484A61K36/538A61K36/575A61K36/718A61K36/754A61K36/758A61K36/808A61K36/8945A61K36/8962A61K36/9068A61K47/44A61K2236/13A61K2236/15A61K2236/19A61K2236/333A61K2236/39A61P11/02A61K2300/00
Inventor 曹京敏
Owner 山东景仲生物科技有限公司
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