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Composition containing active component nervonic acid and preparation method of composition tablets

An active ingredient, nervonic acid technology, applied in the field of biomedicine, can solve problems such as insufficient effect, and achieve the effects of improving microcirculation, activating cell energy metabolism, and improving memory

Active Publication Date: 2018-11-20
北京医万正生物医学研究有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the effect of only using nervonic acid monomers for health care and treatment of the human brain is not significant enough.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049]Example 1. Get 50 grams of nervonic acid, 30 grams of the total extract of Pueraria lobata root, 130 grams of dry powder of lemon juice, and 5 grams of the total extract of scutellaria saponifera, dilute in equal proportions, and mix uniformly to obtain the active composite material, which is set aside. Take 485 grams of maltodextrin, 50 grams of pregelatinized starch, 50 grams of sodium carboxymethyl cellulose, 160 grams of cornstarch, and 40 grams of silicon dioxide, dilute them in equal proportions, and mix them uniformly to obtain the auxiliary material combination, which is set aside. Dilute and mix the above-mentioned active composite material and auxiliary material composite material in equal proportions, and press into tablets at 15±2°C and relative humidity of 40-50% to obtain 1000 g (2000 pieces) of finished product.

Embodiment 2

[0050] Example 2. Take 1.0 g of nervonic acid, 10 g of Pueraria lobata total extract, 60 g of lemon juice dry powder, and 1 g of scutellum total extract, dilute in equal proportions, and mix uniformly to obtain the active composite material, which is set aside. Take 628 grams of maltodextrin, 50 grams of pregelatinized starch, 50 grams of sodium carboxymethylcellulose, 160 grams of cornstarch, and 40 grams of silicon dioxide, dilute them in equal proportions, and mix them uniformly to obtain the auxiliary material combination, which is set aside. Dilute and mix the above-mentioned active composite material and auxiliary material composite material in equal proportions, and press into tablets at 15±2°C and relative humidity of 40-50% to obtain 1000 g (2000 pieces) of finished product.

Embodiment 3

[0051] Example 3. Get 60 grams of nervonic acid, 30 grams of Pueraria lobata total extract, 130 grams of lemon juice dry powder, and 5 grams of scutellum total extract, mix with 85% ethanol and materials, granulate, sieve through 14 meshes, and dry below 40°C. Get the active combination material and set it aside. Take 475 grams of maltodextrin, 50 grams of pregelatinized starch, 50 grams of sodium carboxymethylcellulose, 160 grams of cornstarch, and 40 grams of silicon dioxide, dilute them in equal proportions, and mix them uniformly to obtain the auxiliary material combination, which is set aside. Dilute and mix the above-mentioned active composite material and auxiliary material composite material in equal proportions, and press into tablets at 15±2° C. and relative humidity of 40% to 50% to obtain 1000 g (2000 pieces) of finished product.

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PUM

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Abstract

The invention discloses composition containing active component nervonic acid and a preparation method of composition tablets and belongs to the field of biomedicine. Every 1,000 g of the product comprises active components as follows: 1.0-120 g of nervonic acid, 10-20 g of a radix puerariae total extract, 60-200 g of lemon juice dry powder, 1-10 g of a macaranga adenantha total extract and the balance of auxiliary materials acceptable to corresponding dosage forms. The product is processed with a low-temperature molecular distillation-freezing crystallization-purification and separation technology and a low-temperature granulation and cold pressing technology. The product is stable in quality and low in cost, belongs to the non-toxic class through toxicology safety evaluation and is clinically proved to be safe and effective. The product can improve memory, has exact rehabilitation and treatment effects on patients suffering from Alzheimer's disease, cerebral and cerebellar atrophy and stoke and is superior to nervonic acid monomers.

Description

technical field [0001] The invention belongs to the field of biomedicine. Background technique [0002] Neural acid has health care and therapeutic effects on the human brain. This discovery is a major contribution of science to human health in the past 30 to 40 years. Studies have proved that nervonic acid has the following functions: it is an important substance (white matter) that constitutes the cell membrane in nerve tissue; it is an important source of information transmission media between nerve cells; it is an important source of substances for the growth and repair of brain nerve myelin; Energy metabolism, speed up the repair of damaged nerve cells, promote the growth of new dendrites and lateral buds, establish a new nervous system network, make the signal release and conduction between nerve cells faster and more accurate, promote the recognition ability of cells, and restore nerve endings Activity; it can activate and start the brain cells in the suppressed stat...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/752A61P25/00A61P25/28A61K31/201
CPCA61K31/201A61K36/47A61K36/488A61K36/752A61P25/00A61P25/28A61K2300/00
Inventor 杨为民臧芝儒张玲沈报春陆卿翁稚颖李鲜陈晨施蕊宋流东屈宝良陈彤田昆
Owner 北京医万正生物医学研究有限公司
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