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Mouthwash effervescent tablets as well as preparation method and application thereof

A technology of blisters and parts by mass, applied in the field of mouthwash effervescent tablets and their preparation, can solve the problems of oral hazards, inability to meet requirements, and difficult to store and carry in liquid form, achieves rapid onset of effect, promotes oral health, reduces The effect of preparation cost

Active Publication Date: 2018-11-16
博凯药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] One of the objectives of the present invention is to provide a mouthwash effervescent tablet to improve the existing mouthwash containing chemical reagents, which are harmful to the oral cavity, and the liquid form is not easy to store and carry, and cannot meet the requirements of frequent business trips. technical issues

Method used

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  • Mouthwash effervescent tablets as well as preparation method and application thereof

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preparation example Construction

[0049] The preparation method of golden button extract comprises the steps:

[0050] Take the traditional Chinese medicine Golden Button, cut it into 1-2cm pieces, and then extract it with 3-5 times 30%-99% ethanol at 30°C-90°C for 2-8 hours, reflux extraction 3-5 times, and filter. The filtrate is obtained, and the ethanol is recovered under reduced pressure from the filtrate under the condition of low temperature ≤ 50° C. to obtain the golden button extract.

[0051] By adding honeysuckle extract, tea polyphenols and golden button extract to mouthwash effervescent tablets, the synergistic effect of honeysuckle extract, tea polyphenols, golden button extract, honeysuckle extract and mint ice is antibacterial and anti-inflammatory and better pain relief.

[0052] In a preferred embodiment of the present invention, the acid agent is selected from one or more of tartaric acid, malic acid, fumaric acid or citric acid.

[0053] In a further preferred embodiment of the present in...

Embodiment 1

[0083] This embodiment provides a mouthwash effervescent tablet, comprising 10 parts of mint ice, 720 parts of citric acid, 160 parts of tartaric acid, 1740 parts of sodium carbonate, 302 parts of maltodextrin, 12 parts of sodium chloride, and 175 parts of sodium fluoride , polyethylene glycol 6000 257.3 parts, sucralose 5 parts, lactose 100 parts, silicon dioxide 6.2 parts, mint flavor 17 parts and brilliant blue 0.29 parts.

Embodiment 2

[0085] The present embodiment provides a mouthwash effervescent tablet, comprising 20 parts of mint ice, 730 parts of citric acid, 150 parts of tartaric acid, 1740 parts of sodium carbonate, 292 parts of maltodextrin, 12 parts of sodium chloride, 175 parts of sodium fluoride, 257.3 parts of polyethylene glycol 6000, 5 parts of sucralose, 100 parts of lactose, 6.2 parts of silicon dioxide, 17 parts of mint essence and 0.29 parts of brilliant blue.

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Abstract

The invention provides mouthwash effervescent tablets as well as a preparation method and application thereof, and relates to the technical field of effervescent tablets. The mouthwash effervescent tablets are prepared from the following components in parts by mass: 10 to 25 parts of mentholum, 800 to 1,500 parts of acid agent and 1,500 to 2,000 parts of alkaline agent. The invention solves the technical problems that existing mouthwash contains more ethyl alcohol, has a certain hazard to the oral cavity, and due to a liquid form, is difficult to store and carry so as not to meet the requirements of commercial personnel who frequently go on a business trip. The mouthwash effervescent tablets provided by the invention not only can effectively sterilize, diminish inflammation, alleviate painand stop bleeding, but also have no any toxic and side effects, can effectively promote oral health, meanwhile, is also convenient to carry and store, can be rapidly disintegrated in water, are convenient to take, have a high response speed and can meet the use requirements of commercial personnel who frequently go on a business trip.

Description

technical field [0001] The invention relates to the technical field of effervescent tablets, in particular to a mouthwash effervescent tablet and its preparation method and application. Background technique [0002] With the continuous improvement of living standards in today's society, people's eating habits are gradually changing, coupled with the usual bad living habits, resulting in many oral problems, such as periodontitis, dental caries, bad breath and oral ulcers. There are many ways to prevent and maintain oral health. Traditionally, toothpaste and tooth strips are used to clean the mouth and prevent oral diseases. However, toothpaste or tooth strips are often used to maintain oral hygiene, and the effect is often not good. [0003] Mouthwashes are now withdrawn from the market to prevent and treat oral diseases, which can directly act on the affected area and effectively relieve the pain of oral diseases. However, most mouthwashes contain chemical reagents, which ar...

Claims

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Application Information

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IPC IPC(8): A61K8/34A61K8/9789A61K8/365A61K8/362A61K8/19A61K8/02A61Q11/00A61P1/02
CPCA61K8/0216A61K8/19A61K8/34A61K8/362A61K8/365A61K2800/592A61K2800/5922A61K2800/92A61Q11/00A61K8/9789A61P1/02
Inventor 胡晓娟刘洪生张荣培李跃克
Owner 博凯药业有限公司
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