Double-valve three-pump high performance liquid chromatography system

Abstract

The invention relates to a double-valve three-pump high performance liquid chromatography system, which comprises a solid-phase extraction sample-feeding pump, an external six-way valve, a solid-phaseextraction column, a one-dimensional analysis column, a variable wavelength detector, a two-dimensional capture column, a two-dimensional analysis column, a diode array detector and an internal six-way valve, the solid-phase extraction sample-feeding pump is connected with an automatic sample injector, the automatic sample injector and a waste liquid collecting device, the one-dimensional analysis pump is respectively connected with the fourth port, the sixth port and the eighth port of the external six-way valve; the solid-phase extraction column is connected with the fifth port and the seventh port of the external six-way valve; the one-dimensional analysis column is connected with the ninth port of the external six-way valve and the fourteenth port of the internal six-way valve; the variable wavelength detector and the two-dimensional analysis pump are respectively connected with the fifteenth port and the seventeenth port of the internal six-way valve, the two-dimensional capturecolumn is connected with the sixteenth port and the nineteenth port of the external six-way valve; the two-dimensional analysis column is connected with the eighteenth port of the internal six-way valve and the diode array detector; according to the invention, the sample pretreatment process is simplified, and the analysis efficiency of the sample is improved.

Description

[technical field] [0001] The invention relates to the technical field of high-performance liquid chromatography, in particular to a double-valve and three-pump high-performance liquid chromatography system. [Background technique] [0002] Since the use of chromatography in 1903, various chromatographic techniques have emerged. Among them, high performance liquid chromatography has become the most commonly used separation and detection method due to its advantages such as fast analysis speed, high separation efficiency, high detection sensitivity, automatic detection, and wide application range. It is widely used in the fields of pharmacology, food science, and environmental monitoring. Since the beginning of the 21st century, the development of chromatography technology has gradually matured, and the basic innovation results are very limited, but the technical progress has been going on, especially the applied research related to the industry is still very active. [0003] ...

AI Technical Summary

Problems solved by technology

However, because the pretreatment of the method still requires steps such as saponification, extraction and concentration, the pretreatment process is tedious and complicated, time-consuming and labor-intensive, which greatly affects the analysis efficiency of the sample.

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