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Method for preventing or treating conjunctivitis and herpes zoster palpebral dermatitis and bear gall powder used by method

A technology of bear bile powder and bear bile, which is applied to medical preparations containing active ingredients, powder delivery, and pharmaceutical formulas, etc., and can solve problems such as easy moisture absorption and agglomeration, unstable properties, and easy corruption of bear bile powder

Inactive Publication Date: 2018-09-28
齐光伟
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] CN1311002A (00102073.0, Shi Lixia) discloses a refined bear bile powder and its preparation method, which belongs to the field of pharmacy. Common bear bile powder is easy to absorb moisture and agglomerate, has a sticky tooth feeling, extremely fishy smell, extremely bitter taste, many impurities, and slow absorption. The property is unstable and easy to be corrupted, and the content of active ingredients is low, which limits the application range of bear bile powder. Oral application often adds flavoring agents to reduce the stench

Method used

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  • Method for preventing or treating conjunctivitis and herpes zoster palpebral dermatitis and bear gall powder used by method
  • Method for preventing or treating conjunctivitis and herpes zoster palpebral dermatitis and bear gall powder used by method
  • Method for preventing or treating conjunctivitis and herpes zoster palpebral dermatitis and bear gall powder used by method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0100] Embodiment 1: prepare bear bile powder

[0101] (1) Filtrate the bear bile collected by the tubeless drainage method to obtain the filtrate, add 0.75 times the amount of water to dilute to obtain bear bile fluid, and place it at a temperature of 2-6°C for 12 hours before performing subsequent operations;

[0102] (2) In the mode of bubbling, in step (1) gained bear bile liquid, be charged with nitrogen for 27min, then be charged with carbon dioxide for 18min;

[0103] (3) Pour the bear bile liquid processed through the above operations into the material tray (the depth of the liquid layer is 1.5~2.5cm), and immediately place it in a freeze dryer that has been frozen to -50°C in advance, and freeze it for 3.5 hours; The temperature was raised to -22°C at a rate of 0.3°C and kept for 1 hour; then the temperature was raised to -3°C at a rate of 0.3°C per minute and kept for 2.5 hours; then the temperature was raised to 10°C at a rate of 0.3°C per minute and kept for 4.5 h...

Embodiment 2

[0111] Embodiment 2: prepare bear bile powder

[0112] (1) Filtrate the bear bile collected by the tubeless drainage method to obtain the filtrate, add 0.5 times the amount of water to dilute to obtain the bear bile fluid, and let it stand at a temperature of 2-6° C. for 12 hours before performing subsequent operations;

[0113] (2) In the mode of bubbling, in step (1) gained bear bile liquid, be filled with nitrogen 30min, then be filled with carbon dioxide 15min;

[0114] (3) Pour the bear bile liquid processed through the above operations into the material tray (the depth of the liquid layer is 1.5~2.5cm), and immediately place it in a freeze dryer that has been frozen to -55°C in advance, and freeze it for 3 hours; The temperature was raised to -23°C at a rate of 0.3°C and kept for 1.5 hours; then the temperature was raised to -2°C at a rate of 0.25°C per minute and kept for 2 hours; then the temperature was raised to 12°C at a rate of 0.25°C per minute and kept for 5 hour...

Embodiment 3

[0122] Embodiment 3: prepare bear bile powder

[0123] (1) Filter the bear bile collected by the tubeless drainage method to obtain the filtrate, add 1 times the amount of water to dilute to obtain the bear bile fluid, and let it stand at a temperature of 2-6°C for 12 hours before performing subsequent operations;

[0124] (2) In the mode of bubbling, in step (1) gained bear bile liquid, be filled with nitrogen 25min, then be filled with carbon dioxide 20min;

[0125] (3) Pour the bear bile liquid processed through the above operations into the material tray (the depth of the liquid layer is 1.5~2.5cm), and immediately place it in a freeze dryer that has been frozen to -45°C in advance, and freeze it for 4 hours; The temperature was raised to -20°C at a rate of 0.35°C and kept for 1.2 hours; then the temperature was raised to -2°C at a rate of 0.35°C per minute and kept for 3 hours; then the temperature was raised to 15°C at a rate of 0.34°C per minute and kept for 4 hours; ...

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Abstract

The invention discloses a method for preventing or treating conjunctivitis and herpes zoster palpebral dermatitis, bear gall powder used by the method, and a preparation method of the bear gall powder. The bear gall powder can be used for regulating blood lipid, lowering total cholesterol, preventing cardiovascular and cerebrovascular diseases and preventing atherosclerosis. Materials are subjected to ice crystallization during the preparation of the bear gall powder, and then freeze drying is performed to obtain the freeze-dried bear gall powder which can be called ice-crystalized bear gall powder. The Senbao ice-crystalized bear gall powder does not contain any auxiliary materials and chemical additives, can effectively regulate the blood lipid and lower the total cholesterol, can be effectively used for preventing cardiovascular and cerebrovascular diseases and atherosclerosis and preventing and treating solid tumor and blood system tumor, and can be particularly effectively used for preventing or treating the conjunctivitis and herpes zoster palpebral dermatitis.

Description

technical field [0001] The invention belongs to the technical field of medicine and health products, relates to a bear bile powder prepared by a specific process, and also relates to a preparation method of the bear bile powder. In the process of preparing the bear bile powder, the material is ice-crystallized and then freeze-dried, so that the prepared bear bile powder exhibits excellent technical effects, especially in terms of physical and chemical properties. In particular, the present invention pre-dilutes bear bile powder with a small amount of water, fills it with two kinds of gas, and carries out deep freezing, so that the active ingredients contained in bear bile are in a state of ice crystals, and then sublimated, so that the obtained freeze-dried Bear bile powder can be referred to as ice crystal bear bile powder in the present invention, or can be called ice crystal bear bile powder, or can be called Senbao bear bile powder. Especially the bear bile powder that th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/413A61K9/19A61P3/06A61P9/00A61P9/10A61P35/00A61P35/02A61P7/02A61P37/04A61P39/00A61P27/02A61P31/22A61P1/16A23L33/00
Inventor 齐光伟
Owner 齐光伟
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