Method for Separation and Concentration Control of Melanin and Hemoglobin in Human Skin Slice Images

Abstract

The invention discloses a method for separating melanin and hemachrome in human skin slice images and carrying out concentration control. The method comprises the following steps of: obtaining a humanskin slice RGB color image, and carrying out principal component analysis on signals of R / G / B channels of the image so as to obtain a two-dimensional signal; carrying out two-layer cascade non-negative matrix factorization on the two-dimensional signal to obtain a hybrid matrix, and carrying out dimension raising and statistical transformation on the hybrid matrix; designing a hybrid matrix effectiveness judging constraint condition so as to judge the effectiveness of separation, and if the separation is ineffective, terminating the processing; and designing a weight control factor of the hybrid matrix, and respectively constructing a concentration-adjustable human skin slice melanin or hemachrome concentration distribution image and a comprehensive composite image. According to the method, a two-layer non-negative matrix factorization method and the hybrid matrix effectiveness judging constraint condition are designed, so that the technical problem of bad separation result robustnesscaused by instability of hybrid matrixes in existing melanin and hemachrome separation methods is solved.

Description

Technical field [0001] The present invention belongs to the technical field of digital image processing, and more specifically, relates to a method for separating and regulating the concentration of melanin and hemoglobin of a human skin slice image based on non-negative matrix decomposition. Background technique [0002] Human skin can be divided into three levels from the outside to the inside: epidermis, dermis and subcutaneous fat tissue. In addition, the color of the human skin image taken by a general-purpose RGB camera is mainly determined by the melanin of the epidermis, hemoglobin of the dermis, and the background contour. Among them, the background contour has much less influence on the color rendering effect of the skin image than melanin and hemoglobin. Therefore, if the concentration of melanin and hemoglobin in the skin can be separated, it will help to observe the damage of human skin in depth, which will greatly help the targeted care or treatment of the skin, an...

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Problems solved by technology

Emphatically, in the present invention, a two-layer cascaded non-negative matrix decomposition method and a mixing matrix transformation method are designed, and the validity determination constraint conditions of the mixing matrix are formulated, so as to realize the manipulation and validity judgment of the mixing matrix, and solve the current problem In the separation method of melanin and hemoglobin, there is a technical problem of poor robustness of separation results due to the instability of the mixing matrix

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