Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Extraction method of active components of lycium barbarum and application

An extraction method and a technology of active ingredients, which are applied in the field of extracting active ingredients of wolfberry, can solve the problems of low extraction rate of polysaccharides and flavonoids, large amount of residual waste, difficult to handle, etc., and achieve the effects of improved utilization rate, small size, and convenient portability

Active Publication Date: 2018-08-24
HUNAN NORMAL UNIVERSITY
View PDF4 Cites 4 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In this invention, the filtrate after water extraction is directly purified to separate Lycium barbarum polysaccharides, so that the extraction rate of polysaccharides and flavonoids is reduced, and the amount of remaining waste residue after extracting Lycium barbarum flavonoids and Lycium barbarum polysaccharides is large, difficult to handle, easy to cause waste of resources, and cause environmental damage. pressure

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Extraction method of active components of lycium barbarum and application
  • Extraction method of active components of lycium barbarum and application
  • Extraction method of active components of lycium barbarum and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] 1) Grind black wolfberry after freeze-drying at -10~-20°C into a powder with a particle size of 30 mesh, mix black wolfberry powder with distilled water at a mass volume ratio of 1:20g / ml, and perform ultrasonic extraction at a temperature of 70 ℃, the extraction time is 1.5h, and then filtered to obtain the water-extracted filtrate and the water-extracted filter residue;

[0036] 2) The water-extracted filter residue was mixed with absolute ethanol at a mass volume ratio of 1:10 g / ml, and then microwave-extracted at room temperature for 1.5 hours to obtain ethanol-extracted mixture I;

[0037] 3) After the water extraction filtrate is concentrated and dried, it is mixed with absolute ethanol at a mass volume ratio of 1:5 g / ml, and ultrasonically extracted at 70° C. for 0.5 h to obtain ethanol extraction mixture II;

[0038] 4) Filtering the ethanol extraction mixture I and the ethanol extraction mixture II respectively, mixing and concentrating the obtained two filtrat...

Embodiment 2

[0042] 1) Crush the black wolfberry after freeze-drying at -10~-20°C into a powder with a particle size of 40 mesh, mix the black wolfberry powder and distilled water at a mass volume ratio of 1:10g / ml, and then perform ultrasonic extraction at a temperature of 78 ℃, the extraction time is 2h, and then filtered to obtain the water-extracted filtrate and the water-extracted filter residue;

[0043] 2) The water-extracted filter residue was mixed with absolute ethanol at a mass volume ratio of 1:10 g / ml, and then microwave-extracted at room temperature for 2 hours to obtain ethanol-extracted mixture I;

[0044] 3) After the water extraction filtrate is concentrated and dried, it is mixed with absolute ethanol at a mass volume ratio of 1:6 g / ml, and ultrasonically extracted at 78°C for 1 hour to obtain ethanol extraction mixture II;

[0045] 4) Filtering the ethanol extraction mixture I and the ethanol extraction mixture II respectively, mixing and concentrating the obtained two ...

Embodiment 3

[0049] 1) Crush the black wolfberry after freeze-drying at -10~-20°C into a powder with a particle size of 50 mesh, mix the black wolfberry powder with distilled water at a mass volume ratio of 1:15g / ml, and then perform ultrasonic extraction at a temperature of 80 ℃, the extraction time is 3h, and then filtered to obtain the water-extracted filtrate and the water-extracted filter residue;

[0050] 2) The water-extracted filter residue was mixed with absolute ethanol at a mass volume ratio of 1:15g / ml, and then microwave-extracted at room temperature for 2.5 hours to obtain ethanol-extracted mixture I;

[0051] 3) After the water extraction filtrate is concentrated and dried, it is mixed with absolute ethanol at a mass volume ratio of 1:10 g / ml, and ultrasonically extracted at 80°C for 1.2 hours to obtain ethanol extraction mixture II;

[0052] 4) Filtering the ethanol extraction mixture I and the ethanol extraction mixture II respectively, mixing and concentrating the obtaine...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Particle sizeaaaaaaaaaa
Login to View More

Abstract

The invention discloses an extraction method of active components of lycium barbarum. According to the method, lycium barbarum is subjected to freezing and drying at first and then subjected to ultrasonic aqueous extraction, and then filtering is conducted to obtain an aqueous extraction filtrate and aqueous extraction dregs; the aqueous extraction dregs are subjected to microwave ultrasonic extraction to obtain an ethanol extraction mixture I; the aqueous extraction filtrate is subjected to ultrasonic alcohol extraction to obtain an ethanol extraction mixture II; the ethanol extraction mixture I and the ethanol extraction mixture II are filtered to obtain filtrates respectively, the filtrates are mixed and concentrated to obtain a concentrated liquid, the concentrated liquid is extractedby ethyl acetate, and through column chromatography on silica gel and drying, lycium barbarum flavone is obtained; obtained filtration dregs are mixed and then purified by means of DEAE-cellulose column chromatography, and drying is conducted to obtain lycium barbarum polysaccharide; concentrated dregs are subjected to reflux, concentration, macroporous resin chromatography and drying to obtain lycium barbarum coloring matter. The final extraction rates of lycium barbarum flavone, lycium barbarum polysaccharide and lycium barbarum coloring matter are high, the utilization rate of lycium barbarum is greatly increased, the extraction time is shortened at the same time, and the production cost is remarkably reduced.

Description

technical field [0001] The invention belongs to the technical field of food and medicine, and in particular relates to an extraction method and application of active ingredients of wolfberry. Background technique [0002] Lycium barbarum belongs to Solanaceae (Solanaceae). In the 1970s, Lu Anmin and others investigated the Lycium genus plants in my country and determined 7 germplasm resources of Lycium barbarum in China, including Ningxia Lycium barbarum and Black Lycium barbarum. Lycium barbarum is a rare and precious Chinese herbal medicine with a long history, the same origin of medicine and food, and is well-known both at home and abroad. As early as in the "Shen Nong's Materia Medica", it was listed as the top grade, and it was called "long-term use, light body, not old, cold and heat-resistant". According to traditional Chinese medicine, wolfberry is flat in nature, sweet in taste, slightly bitter, non-toxic, and has the effect of nourishing the liver and lungs. , Yij...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/815A61P1/16A23L33/105A23L5/30
CPCA23V2002/00A61K36/815A61K2236/33A61K2236/331A61K2236/51A61K2236/55A23L5/32A23L5/34A23L33/105A61P1/16A23V2250/21A23V2250/2116A23V2250/51
Inventor 陈嘉勤陈伊琳李娣朱彦彭琪
Owner HUNAN NORMAL UNIVERSITY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com