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Skin care agent containing ginseng extract

A ginseng extraction and skin care agent technology, applied in the field of cosmetics, can solve the problems of ignoring the adverse effects and effects of ginseng extracts, limiting the active effects of ginseng extracts, and not realizing the synergistic effect of interactions

Active Publication Date: 2018-08-17
胡东辉
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0016] However, in the prior art, although it is recognized that ginseng extract can be used as an effective active ingredient in skin care products, it has various effects such as whitening and anti-wrinkle, but it is only aware of its active effect alone, and does not realize its interaction with other active ingredients. interaction and synergistic effect, thus limiting the activity of ginseng extract
[0017] It is also found that in the prior art, the quality evaluation and use of ginseng extracts are mainly based on their total saponin content, rather than based on one or several more active and higher components, and ginseng extracts are ignored. Adverse effects and effects of other trace components in the substance

Method used

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  • Skin care agent containing ginseng extract
  • Skin care agent containing ginseng extract
  • Skin care agent containing ginseng extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0063] Take fresh ginseng (northeast ginseng, purchased from Fusong County, Jilin), wash it with water to remove impurities such as soil, cook the washed fresh ginseng at 90°C for 2 hours to gelatinize the starch, and then dry it at a temperature of 55°C Be 3% to water content, the ginseng after the drying is pulverized into fine powder particle, and the average particle size of powder particle is 0.5mm, uses subcritical extractor (manufactured by Nantong Yichuang Experimental Instrument Co., Ltd.), and extraction solvent is water-ethanol mixing Solvent (volume ratio is 1:1) is extracted time 45 minutes under the temperature of 120 ℃, and pressure is about 8.9MPa in the extraction process, obtains extract, the extract that will collect is freeze-dried at 4 ℃; Column chromatography separation, this separation step comprises: the chromatographic column stuffing used is C18 stationary phase material, and elution phase is the mixture of acetonitrile and distilled water, adopts grad...

Embodiment 2

[0069]Prepare the skin care agent according to the following proportions, in percent by weight: 2.0% of the ginseng extract according to Example 1, 5.0% of 1,4-dipalmitoyl hydroxyproline (purchased from Shanghai Enzyme Biotechnology, referred to as DPA), 1 , 3-butanediol 6.0%, hyaluronic acid 3.0% (the weight ratio of large molecular weight hyaluronic acid, medium molecular weight hyaluronic acid and small molecular weight hyaluronic acid is 2:12:0.2), multivitamin 1.5%, 0.5% p-aminobenzoic acid, olive oil 10%, stearic acid 1.2%, octyldodecyl myristate 3.0%, methyl p-hydroxybenzoate 0.5%, fatty alcohol polyoxyethylene ether 8.0%, and the rest is water. The ginseng extract and 1,4-dipalmitoyl hydroxyproline are mixed with 1,3-butanediol, and then stirred and mixed with other components to prepare a skin care agent. Use the ELISA method to detect the anti-apoptotic effect of the skin care agent ginseng extract of the present invention and 1,4-dipalmitoyl hydroxyproline in epider...

Embodiment 3

[0071] The difference from Example 2 is only that the content of ginseng extract is 1.0%, and the content of 1,4-dipalmitoyl hydroxyproline is 1.0%. Using the ELISA method, the anti-apoptotic effect of the skin care agent ginseng extract and 1,4-dipalmitoyl hydroxyproline in epidermal cells of the present invention was detected.

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Abstract

The invention provides a skin care agent containing a ginseng extract. The skin care agent containing the ginseng extract comprises the following components in percentages by weight: 1.0-20% of the ginseng extract, 0.01-10% of 1,4-dipalmitoyl hydroxyproline, 2.0-15% of 1,3-butanediol, 0.01-5.0% of hyaluronic acid and 1.0-10% of multi-vitamin. The synergistic effect of active ingredients of the skin care agent can be achieved, therefore, the skin care effect is improved, and the cost of the skin care agent is reduced.

Description

technical field [0001] The invention belongs to the field of cosmetics and relates to a skin care agent containing ginseng extract and a preparation method thereof. Background technique [0002] The skin is exposed to various physical and chemical stresses every day, such as ultraviolet rays, dryness, cold, heat, drugs, etc., resulting in impaired skin functions and various aging phenomena of the skin. Dry skin is the main cause of wrinkled skin aging, which includes wrinkles and blemishes. Epidermal wrinkles are called fine wrinkles, which are temporary wrinkles caused by a decrease in the amount of moisture in the epidermis of the stratum corneum due to dry skin. As a method of improving fine lines, cosmetics with a moisturizing effect are generally used. Skin wrinkles are wrinkles caused by ultraviolet rays contained in sunlight and aging. As the mechanism of its formation, it is currently known that ultraviolet rays and aging cause a decrease in collagen synthesis abi...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61K8/49A61K8/73A61Q19/00A61Q17/04A61Q19/08
CPCA61K8/4913A61K8/735A61K8/9789A61K2800/592A61Q17/04A61Q19/00A61Q19/08
Inventor 胡东辉
Owner 胡东辉
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