Alkaline effervescent tablets for treating gout and hyperuricemia
An effervescent tablet, high uric acid technology, applied in the direction of bone diseases, organic active ingredients, medical preparations with non-active ingredients, etc. Addition and subtraction, high cost of granule preparation, to achieve obvious synergistic effect, easy to take, quick effect
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Embodiment 1
[0024] An alkaline effervescent tablet for patients with gout and hyperuricemia, prepared from the following raw materials: 31.5 kg of citric acid, 21 kg of sodium bicarbonate, 3 kg of sodium citrate, 5 kg of potassium citrate, and 4.9 kg of sorbitol , lactose 0.7kg, acerola cherry extract 1.4kg, polyethylene glycol 0.7kg, sucralose 0.4kg, lemon flavor 1.4kg. It can be made into 20,000 pieces.
[0025] Preparation:
[0026] (a) Mix and pulverize citric acid, sorbitol and lactose through an 80-mesh sieve, put them in a mixer, moisten them with polyethylene glycol, make soft materials, wet granulate, blow at 56°C for 55 minutes on an ebullated bed, and dry them Prepare the first granule and keep the whole granule for later use.
[0027] (b) Sodium bicarbonate, sodium citrate and potassium citrate are mixed and pulverized through a 100-mesh sieve, placed in a mixer, wetted with polyethylene glycol to make a soft material, wet granulated, blown at 56°C in an ebullated bed After...
Embodiment 2
[0033] An alkaline effervescent tablet for patients with gout and hyperuricemia, prepared from the following raw materials: 31.5 kg of citric acid, 21 kg of sodium bicarbonate, 8 kg of potassium citrate, 4.9 kg of sorbitol, 0.7 kg of lactose, Acerola cherry extract 1.4kg, polyethylene glycol 0.7kg, sucralose 0.4kg, lemon essence 1.4kg. It can be made into 20,000 pieces.
[0034] Preparation:
[0035] (a) Mix and pulverize citric acid, sorbitol and lactose through an 80-mesh sieve, put them in a mixer, moisten them with polyethylene glycol, make soft materials, wet granulate, blow at 56°C for 55 minutes on an ebullated bed, and dry them Prepare the first granule and keep the whole granule for later use.
[0036] (b) Sodium bicarbonate and potassium citrate are mixed and pulverized through a 100-mesh sieve, placed in a mixer, wetted with polyethylene glycol, made into a soft material, wet granulated, blown at 56°C for 55 minutes on an ebullated bed, and dried to make a soft ma...
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