Preparation method of Gansu capsule

A Gansu capsule and granulator technology, which is applied in the direction of capsule delivery, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve the problem that the active ingredients of the drug cannot be released stably and uniformly, and the drug particles collapse Different disintegration time limits, uneven drug particles, etc., to achieve consistent disintegration time, improve disintegration consistency, and uniform size

Inactive Publication Date: 2018-07-06
SICHUAN YUTUO TIBETAN MEDICINE IND CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the existing manufacturing process of Gansu capsules, the drug granules are uneven, resulting in different disintegration time limits of the drug granule

Method used

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Embodiment Construction

[0027] All features disclosed in this specification, or steps in all methods or processes disclosed, may be combined in any manner, except for mutually exclusive features and / or steps.

[0028] A preparation method of Gansu capsules, comprising the steps of:

[0029] [1] Granulation: From the temporary storage room of raw materials and auxiliary materials, take the root vegetable clear paste powder, root vegetable clear paste, micronized silica gel and talcum powder and check: the barrel paper is correct, the packaging quality, and the material properties meet the regulations. Proportionally add the root-cutting paste powder, micronized silica gel and talcum powder into the one-step granulator, and spray the root-cutting paste into the granulator at the same time as the granulation, and dry the prepared granules until the water content is not more than 3 % (measured by a workshop rapid moisture analyzer, get 5g sample and put it into the rapid moisture analyzer, turn on the po...

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Abstract

The invention belongs to the technical field of drug production and particularly relates to a preparation method of a Gansu capsule. Aiming at the defect of unstable drug efficacy caused by differentdisintegration time limits of drug granules of a Gansu capsule prepared by the prior art, the invention adopts the technical scheme that the preparation method comprises the following steps: (1) granulation: adding a penthorum chinense pursh extract powder, micro-powder silica gel and a talcum powder in a granulating machine in proportion, spraying a penthorum chinense pursh extract powder into the granulating machine in proportion during granulation and finally preparing the drug granules; (2) totally mixing: adding the drug granules prepared in the step (1) in a mixing machine for uniform mixing; (3) filling: filling the capsule with the drug granules mixed in the step (2) and then polishing the capsule to obtain the Gansu capsule. The preparation method provided by the invention is suitable for the production of the Gansu capsule.

Description

technical field [0001] The invention belongs to the technical field of medicine production, and in particular relates to a preparation method of Gansu capsules. Background technique [0002] Root-cut root vegetable, also known as yellow grass, is the dried whole herb of the saxifrage plant root-cut root vegetable. It is an authentic medicinal material in Gulin County, Sichuan Province. The medicine is taken from the Wumeng Mountains at an altitude of about 1,000 meters. The main functions are diuresis and dehumidification, promoting blood circulation and dispelling blood stasis, hemostasis and detoxification. For edema, dysuria, jaundice, leukorrhea, dysentery, amenorrhea, bruises, hematuria, metrorrhagia, sores, carbuncles, poisonous snake bites. [0003] In Tibetan medicine, the extract of the root vegetable is made into capsules, namely Gansu Capsules. In the existing manufacturing process of Gansu capsules, the drug granules are uneven, resulting in different disintegr...

Claims

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Application Information

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IPC IPC(8): A61K36/185A61K9/48A61K47/04A61K47/02A61P7/10A61P1/16A61P15/00A61P1/12A61P29/00A61P13/00A61P7/04A61P17/02A61P39/02
CPCA61K9/1611A61K9/1682A61K36/185A61K2236/15A61K2236/331A61K2236/51A61K2236/53
Inventor 张静波赵学勇江勇康莲莲黄潇
Owner SICHUAN YUTUO TIBETAN MEDICINE IND CO LTD
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